Dept Cardiology, Women's Cardiac Health Program, Radboud University Medical Center, Geert Grooteplein-Zuid 10, route 616, 6525GA, Nijmegen, the Netherlands.
Maturitas. 2019 Jun;124:68-71. doi: 10.1016/j.maturitas.2019.03.021. Epub 2019 Mar 28.
There is an ongoing misperception that women under 60 years of age are at low risk of cardiovascular disease (CVD). As there is an important variation in risk among women in this age group, we need to tailor risk assessment by using additional risk parameters during their life-course. For this, valuable tools are family risk, female-specific risk factors and inflammatory co-morbidities, which can be enriched by measuring the coronary artery calcium (CAC) score using computerized tomography. Depending on the results, we can readily adapt lifestyle advice and preventive treatment to every individual woman. Progress has been made in the recognition of stable and unstable manifestations of ischemic heart disease in middle-aged women. Whereas the traditional cardiovascular risk factors are involved in classic obstructive coronary disease, female-specific risk variables, inflammatory co-morbidities and psychosocial stress are also involved in other types of ischemic disease. We therefore need a more sex- and gender-sensitive way to look at women's cardiovascular health.
有一种持续存在的误解认为，60 岁以下的女性患心血管疾病（CVD）的风险较低。由于该年龄段的女性存在重要的风险差异，因此我们需要在其整个生命周期中使用其他风险参数来定制风险评估。为此，可以使用计算机断层扫描测量冠状动脉钙（CAC）评分来丰富家族风险、女性特有的危险因素和炎症合并症等有价值的工具。根据结果，我们可以轻松地为每个个体女性调整生活方式建议和预防治疗。在识别中年女性缺血性心脏病的稳定和不稳定表现方面已经取得了进展。虽然传统的心血管危险因素与典型的阻塞性冠状动脉疾病有关，但女性特有的危险因素、炎症合并症和心理社会压力也与其他类型的缺血性疾病有关。因此，我们需要一种更具性别敏感性的方法来关注女性的心血管健康。
