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一类用于磁生物学研究的新信号。

A new class of signals for magnetobiology research.

机构信息

Department of Physics and Instituto de Física Aplicada (INFAP), Universidad Nacional de San Luis-CONICET, San Luis, Argentina.

出版信息

Sci Rep. 2019 May 16;9(1):7478. doi: 10.1038/s41598-019-43984-z.

DOI:10.1038/s41598-019-43984-z
PMID:31097756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6522507/
Abstract

The great majority of experimental and theoretical studies in magnetobiology explored and tried to explain bioeffects on organisms (ranging from bacteria to humans) upon exposure to variable (AC) magnetic fields (MF) with a pure sinusoidal waveform, typically combined with a static (DC) component. In this report, a new class of signals is presented and posed as a relevant candidate for research in magnetobiology. The proposed signals are derived within the classic theory of the precession of a magnetic moment in a DC + AC MF in a parallel configuration. They display a frequency modulation such that the phase change per unit time of the applied AC field is, at all times, identical to that of the precession of the magnetic moment to which the field was tuned (considering its gyromagnetic ratio). In other words, applied AC field and precession of the 'engaged' magnetic moment are phase-locked. These phase-locked frequency modulated (PLFM) signals are discussed in the context of current literature, and possible future experimental and theoretical developments are suggested.

摘要

绝大多数磁生物学的实验和理论研究都探索并试图解释生物体(从细菌到人类)在暴露于具有纯正弦波形的时变(交流)磁场(MF)时的生物效应,通常与静态(直流)分量相结合。在本报告中,提出了一类新的信号,并将其作为磁生物学研究的一个相关候选对象。所提出的信号是在直流+交流 MF 中磁矩进动的经典理论内导出的,其配置为平行。它们显示出频率调制,使得单位时间内施加的交流场的相位变化始终与被调谐(考虑其旋磁比)的磁矩的进动相位相同。换句话说,施加的交流场和“参与”磁矩的进动相位锁定。这些相位锁定的调频(PLFM)信号在当前文献的背景下进行了讨论,并提出了可能的未来实验和理论发展方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b0f/6522507/36afe53f9b1f/41598_2019_43984_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b0f/6522507/0e26a8ef3689/41598_2019_43984_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b0f/6522507/36afe53f9b1f/41598_2019_43984_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b0f/6522507/0e26a8ef3689/41598_2019_43984_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b0f/6522507/36afe53f9b1f/41598_2019_43984_Fig2_HTML.jpg

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Bioelectromagnetics. 2017 Jan;38(1):41-52. doi: 10.1002/bem.22011. Epub 2016 Nov 8.
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Low-Cost High-Performance MRI.低成本高性能磁共振成像
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The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer.钙调蛋白在细胞增殖、程序性细胞死亡、自噬及癌症中的多种作用
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The detection threshold for extremely low frequency magnetic fields may be below 1000 nT-Hz in mice.小鼠对极低频磁场的检测阈值可能低于1000纳特斯拉-赫兹。
Bioelectromagnetics. 2011 Oct;32(7):561-9. doi: 10.1002/bem.20661. Epub 2011 Mar 4.
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A Lorentz model for weak magnetic field bioeffects: part I--thermal noise is an essential component of AC/DC effects on bound ion trajectory.一种用于弱磁场生物效应的洛伦兹模型:第一部分——热噪声是交流/直流对束缚离子轨迹影响的重要组成部分。
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