Suppr超能文献

沙特阿拉伯西南部一家三级医院的贝切特病表现和护理结果。

Behçet's disease presentations and care outcomes in a tertiary hospital in south-western Saudi Arabia.

机构信息

College of Medicine, King Khalid University, Abha, Saudi Arabia.

Aseer Central Hospital, Abha, Saudi Arabia.

出版信息

Int J Rheum Dis. 2019 Aug;22(8):1466-1473. doi: 10.1111/1756-185X.13598. Epub 2019 May 17.

Abstract

AIM

To study the clinical presentations of Behçet's disease in patients visiting a tertiary hospital in south-western Saudi Arabia.

PATIENTS AND METHODS

Forty-seven patients with Behçet's disease attending the Rheumatology Department at Asser Central Hospital, Saudi Arabia were recruited into the study. The study was conducted over a period of 5 years from January 2012 to July 2017. Medical records of the patients were reviewed to analyze the frequency of different clinical manifestations.

RESULTS

The study had 26 men and 21 women. The mean age of the patients was 37.11 ± 11.9 years (range <30-60 years). Frequency of main clinical manifestations in these patients included 89.4% (42/47) oral ulcers, 80.9% (38) genital ulcers, 55.3% (26/47) ocular complications, 55.3% arthralgia (26/47), 31.9% arthritis (15/47), 36% neurological complications (17/47), 34% gastrointestinal involvement (16), 17% pulmonary complication (8/47), cutaneous lesions in the form of skin pustules were found in 31.9% of cases and erythema only in 4.3% of patients. Deep venous thrombosis was observed in 66.6% of patients. About 96% of patients showed improvement with drugs. Only 2 patients died during the study period.

CONCLUSION

Behçet's disease showed higher male predominance in south-western Saudi Arabia, similar to other Middle-Eastern countries. The clinical characteristics are comparable to different studies reported from other countries. Regarding the care outcome, the majority of patients were cured using oral corticosteroids and other immunosuppressive drugs.

摘要

目的

研究沙特阿拉伯西南部一家三级医院就诊的贝切特病患者的临床表现。

方法

在沙特阿拉伯 Asser 中央医院风湿病科就诊的 47 例贝切特病患者纳入本研究。研究时间为 2012 年 1 月至 2017 年 7 月,共 5 年。对患者的病历进行回顾性分析,以分析不同临床表现的频率。

结果

研究中有 26 名男性和 21 名女性。患者的平均年龄为 37.11±11.9 岁(范围为 <30-60 岁)。这些患者的主要临床表现包括 89.4%(42/47)口腔溃疡、80.9%(38)生殖器溃疡、55.3%(26/47)眼部并发症、55.3%(26/47)关节痛、31.9%(15/47)关节炎、36%(17/47)神经并发症、34%(16)胃肠道受累、17%(8/47)肺部并发症、31.9%(15/47)皮肤病变为脓疱、4.3%(2/47)皮肤红斑。66.6%的患者存在深静脉血栓形成。约 96%的患者经药物治疗后病情改善。研究期间仅 2 例患者死亡。

结论

贝切特病在沙特阿拉伯西南部男性患病率较高,与其他中东国家相似。临床特征与其他国家报道的不同研究相似。在治疗结果方面,大多数患者使用口服皮质类固醇和其他免疫抑制剂治疗后痊愈。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验