a División de Estudios de Posgrado (Tecnología Farmacéutica), Facultad de Estudios Superiores Cuautitlán , Universidad Nacional Autónoma de México , Cuautitlán Izcalli , Mexico.
Drug Dev Ind Pharm. 2019 Sep;45(9):1389-1402. doi: 10.1080/03639045.2019.1620270. Epub 2019 Jun 20.
In general, the systems intended for the treatment and recovery of wounds, seek to act as a coating for the damaged area, maintaining an adequate level of humidity, reducing pain, and preventing the invasion and proliferation of microorganisms. Although many of the systems that are currently on the market meet the purposes mentioned above, with the arrival of nanotechnology, it has sought to improve the performance of these coatings. The variety of nano-systems that have been proposed is very extensive, including the use of very different materials (natural or synthetic) ranging from polymers or lipids to systems derived from microorganisms. With the objective of improving the performance of the systems, seeking to combat several of the problems that arise in a wound, especially when it is chronic, these materials have been combined, giving rise to nanocomposites or scaffolds. In recent years, the interest in the development of systems for the treatment of wounds is notable, which is reflected in the increase in publications related to the subject. Therefore, this document presents generalities of systems involving nanocarriers, mentioning some examples of representative systems of each case.
一般来说，用于治疗和恢复伤口的系统旨在作为受损区域的涂层，保持适当的湿度水平，减轻疼痛，并防止微生物的入侵和增殖。尽管目前市场上的许多系统都满足了上述目的，但随着纳米技术的到来，它已经寻求提高这些涂层的性能。已经提出的纳米系统种类非常广泛，包括使用非常不同的材料（天然或合成），范围从聚合物或脂质到源自微生物的系统。为了提高系统的性能，寻求解决伤口中出现的多种问题，尤其是慢性伤口，这些材料已经结合在一起，形成了纳米复合材料或支架。近年来，人们对开发伤口治疗系统的兴趣显著增加，这反映在与该主题相关的出版物的增加上。因此，本文介绍了涉及纳米载体的系统的概况，提到了每种情况下一些有代表性的系统示例。
