采用称重拭子法研究月经周期中期宫颈微生物菌群及其与精子穿透宫颈黏液试验结果的可能相关性。
The midcycle cervical microbial flora as studied by the weighed-swab method, and its possible correlation with results of sperm cervical mucus penetration tests.
作者信息
Tan S L, Scammell G, Houang E
出版信息
Fertil Steril. 1987 Jun;47(6):941-6. doi: 10.1016/s0015-0282(16)59227-9.
Infertile couples undergoing routine investigation for infertility were randomly selected for the study. A quantitative method using weighed swabs was found satisfactory for the study of microbial flora in the midcycle cervical mucus. In 6 of the 20 women, the midcycle cervical mucus was hostile in the sperm cervical mucus penetration tests. The total bacterial counts and the number of species (average, 2.5) isolated from the hostile mucus were significantly greater than those from the receptive mucus (average, 1.3). Only normal vaginal/cervical flora was isolated. Ureaplasma urealyticum was found more frequently in patients undergoing clomiphene citrate therapy (6/10 versus 0/9, P less than 0.03, Fischer's Exact test).
对因不育症接受常规检查的不孕夫妇进行随机选择以进行该研究。发现一种使用称重拭子的定量方法对于研究月经周期中期宫颈黏液中的微生物菌群是令人满意的。在20名女性中的6名中，月经周期中期宫颈黏液在精子-宫颈黏液穿透试验中表现为不利。从不利黏液中分离出的细菌总数和种类数量（平均2.5种）显著高于从有利黏液中分离出的（平均1.3种）。仅分离出正常的阴道/宫颈菌群。解脲脲原体在接受枸橼酸氯米芬治疗的患者中更常见（6/10对比0/9，P小于0.03，Fisher精确检验）。
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