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浅部皮肤真菌病患者的生活质量和心理发病情况。

Quality of life and psychological morbidity in patients with superficial cutaneous dermatophytosis.

机构信息

Departments of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Mycoses. 2019 Aug;62(8):680-685. doi: 10.1111/myc.12930. Epub 2019 Jun 17.

Abstract

We are facing an onslaught of chronic and recurrent dermatophytosis in epidemic proportions never encountered previously. There is a dearth of studies assessing the quality of life (QoL) and psychological morbidity in patients with superficial dermatophytosis. Our aim was to assess QoL and psychological morbidity in a sample of Indian patients suffering from dermatophytosis by using Dermatology Life Quality Index (DLQI) questionnaire and General Health Questionnaire (GHQ), respectively. This was a single-centre, cross-sectional study where consecutive patients of first episode, chronic or recurrent dermatophytosis were invited to participate. In addition to DLQI and GHQ12, patients' demographic data, duration and symptoms of dermatophyte infection, were also documented and recorded in the case record form. We recruited 196 patients who satisfied the inclusion criteria. The mean total DLQI score was 13.41 ± 7.56 (range 0-30). The main items in the questionnaire influenced by the disease were "symptoms and feelings," followed by "daily activities," "leisure" and "personal relationships." Age of the patient and body surface area involved had a significant impact on the QoL in our study (P ≤ 0.05). The mean GHQ-12 score was 16.98; 84.9% of patients had a score higher than or equal to 12 indicating significant psychological distress. GHQ-12 was found to have significant correlation with the DLQI score. Quality of life issues and psychosocial aspect should be considered while managing dermatophytosis as education about the disease, its management and prognosis may go a long way in improving the adherence to treatment and overall outcome in these patients.

摘要

我们正面临着前所未有的、大规模流行的慢性和复发性皮肤癣菌病的侵袭。目前,评估浅部皮肤癣菌病患者生活质量(QoL)和心理发病率的研究很少。我们的目的是使用皮肤病生活质量指数(DLQI)问卷和一般健康问卷(GHQ)分别评估印度患者的生活质量和心理发病率。这是一项单中心、横断面研究,邀请了首次发作、慢性或复发性皮肤癣菌病的连续患者参与。除了 DLQI 和 GHQ12 之外,还记录了患者的人口统计学数据、皮肤癣菌感染的持续时间和症状,并将其记录在病例记录表中。我们招募了 196 名符合纳入标准的患者。平均总 DLQI 得分为 13.41 ± 7.56(范围 0-30)。问卷中受疾病影响的主要项目是“症状和感觉”,其次是“日常活动”、“休闲”和“人际关系”。在我们的研究中,患者的年龄和受累体表面积对生活质量有显著影响(P ≤ 0.05)。平均 GHQ-12 评分为 16.98;84.9%的患者得分高于或等于 12,表明存在明显的心理困扰。GHQ-12 与 DLQI 评分有显著相关性。在治疗皮肤癣菌病时应考虑生活质量问题和社会心理方面,因为关于疾病的教育、其管理和预后可能会极大地改善这些患者对治疗的依从性和整体结局。

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