Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
Trends Biotechnol. 2019 Aug;37(8):795-796. doi: 10.1016/j.tibtech.2019.04.014. Epub 2019 May 15.
A critical aspect in bioprinting is the formulation of bioactive inks. A recent breakthrough in bioink design (Qian et al. Nano Lett. 2019; https://doi.org/10.1021/acs.nanolett.9b00066) enables the direct writing of catalytically active microorganisms with unprecedented cell loading, tunable structural properties, and long-term activity. This strategy will create possibilities for bottom-up design and integration of functional living systems.
生物打印的一个关键方面是生物活性墨水的配方。最近在生物墨水设计方面的突破(Qian 等人,Nano Lett. 2019;https://doi.org/10.1021/acs.nanolett.9b00066)使得具有前所未有的细胞负载、可调结构特性和长期活性的催化活性微生物的直接写入成为可能。该策略将为功能生物系统的自下而上设计和集成创造可能性。