Department of Physical Therapy, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB, Canada.
Department of Rheumatology and Rehabilitation, Faculty of Medicine, Assiut University, Assiut, Egypt.
Phys Sportsmed. 2019 Nov;47(4):463-470. doi: 10.1080/00913847.2019.1623995. Epub 2019 Jun 5.
: Individuals with rheumatoid arthritis (RA) have increased risk of cardiovascular disease (CVD). Lifestyle factors such as prolonged sedentary behavior (SB) and reduced physical activity (PA) may heighten the risk of CVD. The objective of the study was to investigate the role of SB and PA as predictors for long-term CVD risk in RA patients.: A subsample of 273 people diagnosed with RA was extracted from the 2003-2006 National Health and Nutrition Examination Survey and included in this cross-sectional study. Valid accelerometry data were categorized into sedentary behavior, very light, light, and moderate-to-vigorous physical activity. Functional limitations were assessed using a physical function questionnaire. The Framingham risk score (FRS) was used to calculate 10-year CVD risk. Regression models were used to examine the relationships between SB, PA, and 10-year CVD risk while controlling for potential confounders.: Participants spent an average of 9 h/day sedentary, 4 h in very light PA, 1 h in light PA, and 0.4 h in moderate-to-vigorous PA. Greater sedentary time was associated with higher 10-year CVD risk (= 0.019). Increased daily PA, at all intensities, was inversely associated with 10-year CVD risk (< 0.01). In the fully adjusted regression model, associations between 10-year CVD risk and SB (β = 0.31, R = 0.27, < 0.01), very light PA (β = -0.19, R = 0.26, < 0.01), light PA (β = -0.16, R = 0.25, < 0.01), and moderate-to-vigorous PA (β = -0.15, R = 0.25, < 0.01) remained significant.: Strategies for decreasing SB and increasing PA should be explored with individuals with RA in order to decrease long-term CVD risk.
: 类风湿关节炎（RA）患者发生心血管疾病（CVD）的风险增加。久坐行为（SB）时间延长和身体活动（PA）减少等生活方式因素可能会增加 CVD 风险。本研究的目的是探讨 SB 和 PA 作为 RA 患者长期 CVD 风险预测因子的作用。: 从 2003-2006 年全国健康和营养调查中提取了诊断为 RA 的 273 人的亚样本，并将其纳入本横断面研究。有效的加速度计数据被分为久坐行为、极轻、轻和中等到剧烈的身体活动。使用身体功能问卷评估功能限制。Framingham 风险评分（FRS）用于计算 10 年 CVD 风险。回归模型用于检查 SB、PA 与 10 年 CVD 风险之间的关系，同时控制潜在的混杂因素。: 参与者平均每天久坐 9 小时，极轻活动 4 小时，轻活动 1 小时，中等到剧烈活动 0.4 小时。久坐时间越长，10 年 CVD 风险越高（= 0.019）。每天增加任何强度的 PA 都与 10 年 CVD 风险呈负相关（<0.01）。在完全调整的回归模型中，10 年 CVD 风险与 SB（β=0.31，R=0.27，<0.01）、极轻 PA（β=-0.19，R=0.26，<0.01）、轻 PA（β=-0.16，R=0.25，<0.01）和中等到剧烈 PA（β=-0.15，R=0.25，<0.01）之间的关联仍然显著。: 应探索减少 RA 患者 SB 和增加 PA 的策略，以降低长期 CVD 风险。
