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mRNA 前体剪接,再探。

pre-mRNA splicing, revisited.

机构信息

Lawrence Berkeley National Laboratory.

出版信息

Blood. 2019 May 23;133(21):2250-2251. doi: 10.1182/blood-2019-03-901108.

Abstract

In this issue of , Ji et al have identified a novel regulatory mechanism that ensures proper splicing of human pre-messenger RNA (pre-mRNA).

摘要

本期 ,纪等人发现了一种确保人类 前信使 RNA(pre-mRNA)正确剪接的新型调控机制。

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本文引用的文献

1
A cytosine-rich splice regulatory determinant enforces functional processing of the human gene transcript.
Blood. 2019 May 23;133(21):2338-2347. doi: 10.1182/blood-2018-12-891408. Epub 2019 Mar 4.
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Predicting Splicing from Primary Sequence with Deep Learning.
Cell. 2019 Jan 24;176(3):535-548.e24. doi: 10.1016/j.cell.2018.12.015. Epub 2019 Jan 17.
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J Appl Genet. 2018 Aug;59(3):253-268. doi: 10.1007/s13353-018-0444-7. Epub 2018 Apr 21.
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Curr Opin Hematol. 2017 May;24(3):215-221. doi: 10.1097/MOH.0000000000000329.
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Genome Res. 2011 Oct;21(10):1563-71. doi: 10.1101/gr.118638.110. Epub 2011 Jul 12.
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EMBO J. 2011 May 27;30(13):2622-33. doi: 10.1038/emboj.2011.171.
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