Department of Obstetrics and Gynecology, the Edith Wolfson Medical Center, Holon, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, P.O. Box 5, 58100, Tel Aviv, Israel.
Int Urogynecol J. 2020 Feb;31(2):385-389. doi: 10.1007/s00192-019-03979-w. Epub 2019 May 23.
Pelvic organ prolapse (POP) and lower urinary tract symptoms (LUTs), in addition to cervical incompetence, have a multifactorial etiology. Connective tissue disorders are common risk factors in both entities. The objective of this study was to compare long-term urinary and pelvic organ prolapse-related symptoms in patients who experienced cervical incompetence and those who did not.
In this historical prospective cohort, analysis of cervical incompetence cases from one medical center between 2006 and 2009 were compared with a matched control group. All cases included a minimum 7-year follow-up. Symptoms of urinary and prolapse-related complaints during follow-up were evaluated based on the Pelvic Floor Distress Inventory-20 questionnaire.
The study group comprised 37 women who experienced cervical incompetence matched to 34 consecutive controls. There was no difference between the groups in demographic or obstetric characteristics, except for a higher cesarean section rate and earlier deliveries among women with cervical incompetence. On assessment of patient's symptoms, during follow-up, the average Pelvic Organ Prolapse Distress Inventory-6 score was significantly higher in patients who experienced cervical incompetence than in controls (15.0 ± 26.1 vs 1.7 ± 7.1 respectively, p = 0.034). Urinary complaints, as reflected by the Urinary Distress Inventory-6 index, were also more common in women with cervical incompetence (17.9 ± 19.1 vs 3.9 ± 7.3 p = 0.027).
Women with a history of cervical incompetence experienced a higher rate of pelvic organ prolapse and urinary symptoms compared with women who had no cervical insufficiency.
盆腔器官脱垂（POP）和下尿路症状（LUTS）除了宫颈机能不全外，还有多种病因。结缔组织疾病是这两种疾病的常见危险因素。本研究的目的是比较经历过宫颈机能不全和未经历过宫颈机能不全的患者的长期尿和盆腔器官脱垂相关症状。
在这项历史性前瞻性队列研究中，对 2006 年至 2009 年间一家医疗中心的宫颈机能不全病例进行分析，并与匹配的对照组进行比较。所有病例均随访至少 7 年。根据盆腔器官脱垂窘迫问卷-20 评估随访期间的尿和脱垂相关症状。
研究组包括 37 名经历过宫颈机能不全的女性，与 34 名连续对照组相匹配。除了宫颈机能不全患者的剖宫产率和分娩更早外，两组在人口统计学和产科特征方面无差异。在评估患者症状时，在随访期间，经历过宫颈机能不全的患者的盆腔器官脱垂窘迫问卷-6 评分明显高于对照组（分别为 15.0±26.1 和 1.7±7.1，p=0.034）。反映在尿窘迫问卷-6 指数上的尿主诉，在宫颈机能不全的患者中也更为常见（17.9±19.1 和 3.9±7.3，p=0.027）。
与没有宫颈功能不全的女性相比，有宫颈机能不全病史的女性经历盆腔器官脱垂和尿症状的发生率更高。
