Babayan V K
Lipids. 1987 Jun;22(6):417-20. doi: 10.1007/BF02537271.
Lipids are an essential component of our body composition and necessary in our daily food intake. Conventional fats and oils are composed of glycerides of long chain fatty acids and are designated as long chain triglycerides (LCT). Body fat as well as the fats and oils in our daily intake fall into this category. In enteral and parenteral hyperalimentation, we can identify such LCT fats and oils. Soy, corn, safflower and sunflowerseed oils are typical of the LCT oils. In the search for alternative noncarbohydrate fuels, medium chain triglycerides (MCT) are unique and have established themselves in the areas of malabsorption syndrome cases and infant care and as a high energy, rapidly available fuel. Structure lipids with a MCT backbone and linoleic acid built into the triglyceride molecule have been developed to optimize the triglyceride structure that is best for patients, particularly the critically ill. Structured lipids with built-in essential fatty acid components or other polyunsaturated fatty acids promise greater flexibility in patient care and nitrogen support.
脂质是人体组成的重要成分,也是日常食物摄入所必需的。传统的油脂由长链脂肪酸甘油酯组成,被称为长链甘油三酯(LCT)。人体脂肪以及日常摄入的油脂都属于这一类。在肠内和肠外高营养中,我们可以识别出此类LCT油脂。大豆油、玉米油、红花油和葵花籽油是典型的LCT油。在寻找替代非碳水化合物燃料的过程中,中链甘油三酯(MCT)独具特色,并已在吸收不良综合征病例、婴儿护理领域确立了自身地位,且作为一种高能量、快速可用的燃料。已研发出以MCT为骨架、在甘油三酯分子中嵌入亚油酸的结构脂质,以优化对患者(尤其是重症患者)最为有利的甘油三酯结构。含有必需脂肪酸成分或其他多不饱和脂肪酸的结构化脂质有望在患者护理和氮支持方面提供更大的灵活性。