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美国成年烟民戒烟咨询、处方药物使用及相关费用的全国趋势。

National Trends in Cessation Counseling, Prescription Medication Use, and Associated Costs Among US Adult Cigarette Smokers.

机构信息

St Luke's Hospital, Department of Medicine, Chesterfield, Missouri.

Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

JAMA Netw Open. 2019 May 3;2(5):e194585. doi: 10.1001/jamanetworkopen.2019.4585.

Abstract

IMPORTANCE

Cigarette smoking is the leading cause of preventable disease and death in the United States. When used separately or in combination, smoking cessation counseling and cessation medications have been associated with increased cessation rates.

OBJECTIVES

To present trends in self-reported receipt of physician advice to quit smoking and in use of prescription smoking cessation medication along with their associated expenditures among a nationally representative sample of active adult smokers in the United States.

DESIGN, SETTING, AND PARTICIPANTS: This repeated cross-sectional study of US adults aged 18 years or older was conducted from July 5, 2018, through August 15, 2018. Data were collected between January 1, 2006, and December 31, 2015, from the Medical Expenditure Panel Survey, an annual US survey of individuals and families, health care personnel, and employers. Participants (n = 29 106) were noninstitutionalized civilians who were randomly drawn from the respondents of the previous year's National Health Interview Survey. Multivariable logistic regression models were used to examine the associations between sociodemographic factors and receipt of physician cessation advice and use of cessation prescription medication. A 2-part econometric model was used to assess health care expenditures.

MAIN OUTCOMES AND MEASURES

Trends in self-reported receipt of physician advice to quit and uptake of prescription smoking cessation medications with associated total and out-of-pocket expenditures.

RESULTS

The study sample consisted of 29 106 participants, with a mean (SD) age of 57 (10) years and a composition of 13 670 women (47.0%). The results were weighted to provide estimates for 31.2 million active adult cigarette smokers. The proportion of smokers who reported receiving physician advice to quit increased from 60.2% (95% CI, 58.5%-62.0%) in 2006 to 2007 to 64.9% (95% CI, 62.8%-66.9%) in 2014 to 2015, with a P for trend = .001. The odds of receiving physician cessation advice was statistically significantly higher in women (odds ratio [OR], 1.50; 95% CI, 1.39-1.59) and lower among uninsured participants (OR, 0.58; 95% CI, 0.52-0.65). Overall, prescription smoking cessation medication use decreased with a corresponding reduction in total expenditures from $146 million (out-of-pocket cost, $46 million) in 2006 to 2007 to $73 million (out-of-pocket cost, $9 million) in 2014 to 2015. Male (odds ratio [OR], 0.78; 95% CI, 0.66-0.91), uninsured (OR, 0.58; 95% CI, 0.41-0.83), and racial/ethnic minority (African American: OR, 0.51 [95% CI, 0.38-0.69]; Asian: OR, 0.31 [95% CI, 0.10-0.93]; Hispanic: OR, 0.53 [95% CI, 0.36-0.78]) participants were less likely to use prescription smoking cessation medications.

CONCLUSIONS AND RELEVANCE

The lower rates of delivery of physician advice to quit smoking and the lower uptake of known prescription smoking cessation medications among men, younger adults, uninsured individuals, racial/ethnic minority groups, and those without smoking-associated comorbidities may be associated with the higher smoking rates among these subgroups despite an all-time low prevalence of smoking in the United States; this finding calls for a more targeted implementation of smoking cessation guidelines.

摘要

重要提示

在美国,吸烟是可预防疾病和死亡的主要原因。单独或联合使用戒烟咨询和戒烟药物已被证明可提高戒烟率。

目的

呈现美国活跃成年吸烟者自我报告接受医生戒烟建议的趋势,以及使用处方戒烟药物的情况,同时报告相关支出。

设计、地点和参与者:这是一项在美国成年人中的重复横断面研究,参与者年龄为 18 岁或以上,于 2018 年 7 月 5 日至 8 月 15 日进行。数据来自于 2006 年 1 月 1 日至 2015 年 12 月 31 日期间的医疗保险支出调查,这是一项针对个人和家庭、医疗保健人员和雇主的年度美国调查。参与者(n=29106)是非机构化的平民,他们是前一年全国健康访谈调查的回复者中随机抽取的。使用多变量逻辑回归模型来检查社会人口因素与接受医生戒烟建议和使用戒烟处方药之间的关联。使用两部分计量经济学模型评估医疗保健支出。

主要结果和措施

自我报告接受医生戒烟建议和使用处方戒烟药物的趋势,以及相关的总支出和自付支出。

结果

研究样本包括 29106 名参与者,平均(SD)年龄为 57(10)岁,其中 13670 名女性(47.0%)。结果经过加权处理,以提供 3120 万活跃成年吸烟者的估计值。报告接受医生戒烟建议的吸烟者比例从 2006 年至 2007 年的 60.2%(95%置信区间,58.5%-62.0%)上升到 2014 年至 2015 年的 64.9%(95%置信区间,62.8%-66.9%),趋势检验 P 值=0.001。女性接受医生戒烟建议的几率明显更高(比值比[OR],1.50;95%置信区间,1.39-1.59),而未参保者的几率则较低(OR,0.58;95%置信区间,0.52-0.65)。总体而言,处方戒烟药物的使用减少了,总支出从 2006 年至 2007 年的 1.46 亿美元(自付费用 4600 万美元)减少到 2014 年至 2015 年的 7300 万美元(自付费用 900 万美元)。男性(OR,0.78;95%置信区间,0.66-0.91)、未参保者(OR,0.58;95%置信区间,0.41-0.83)和少数族裔/种族群体(非裔美国人:OR,0.51 [95%置信区间,0.38-0.69];亚裔美国人:OR,0.31 [95%置信区间,0.10-0.93];西班牙裔美国人:OR,0.53 [95%置信区间,0.36-0.78])参与者使用处方戒烟药物的可能性较低。

结论和相关性

男性、年轻成年人、未参保者、少数族裔/种族群体和没有与吸烟相关的合并症的人,接受医生戒烟建议和使用已知处方戒烟药物的比例较低,尽管美国吸烟率创历史新低,但这些亚组的吸烟率仍然较高,这可能与这一现象有关;这一发现呼吁更有针对性地实施戒烟指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d9a/6632149/63eb3c97b3fd/jamanetwopen-2-e194585-g001.jpg

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