Cai Lemei, Dong Jing, Wang Yiru, Chen Xi
Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, P. R. China.
State Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen, Fujian, P. R. China.
Electrophoresis. 2019 Aug;40(16-17):2041-2049. doi: 10.1002/elps.201800531. Epub 2019 May 31.
Surface-enhanced Raman scattering (SERS) greatly expands the applications of Raman spectroscopy and is a promising technique for food safety, environmental analysis, and public safety. Thin-film microextraction (TFME) provides an efficient sample preparation method for SERS to improve its selectivity and detection efficiency. This review comprehensively describes the development and applications of SERS and TFME, including the history, mechanisim, and active substrate of SERS and the theory, device, forms, and practical applications of TFME. The applications of TFME-SERS in food safety and environment monitoring are discussed, which could improve their advantages. TFME extracts and enriches the target analytes to eliminate the interfering substance, providing a facial way for SERS to analyze the target analytes in complex matrices. The development of TFME-SERS technology not only expands the application range of TFME, but greatly improves the anti-interference ability and detection sensitivity of SERS. Thus, the established methods are fast, convenient, and highly sensitive. This technology is potential to be applied in the on-site and real-time detection.
表面增强拉曼散射（SERS）极大地扩展了拉曼光谱的应用范围，是一种在食品安全、环境分析和公共安全领域颇具前景的技术。薄膜微萃取（TFME）为SERS提供了一种高效的样品前处理方法，以提高其选择性和检测效率。本文综述全面描述了SERS和TFME的发展与应用，包括SERS的历史、机理和活性基底，以及TFME的理论、装置、形式和实际应用。讨论了TFME-SERS在食品安全和环境监测中的应用，这可以提升它们的优势。TFME萃取并富集目标分析物以消除干扰物质，为SERS分析复杂基质中的目标分析物提供了一条简便途径。TFME-SERS技术的发展不仅扩大了TFME的应用范围，还极大地提高了SERS的抗干扰能力和检测灵敏度。因此，所建立的方法快速、便捷且高度灵敏。该技术有潜力应用于现场和实时检测。
