Hu Hui, Xiao Hong, Zheng Yi, Yu Bo Bonnie
Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, FL, USA.
Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, FL, USA.
Spat Spatiotemporal Epidemiol. 2019 Jun;29:43-50. doi: 10.1016/j.sste.2019.03.002. Epub 2019 Apr 6.
Disparities in hypertensive disorders of pregnancy (HDP) exist among racial and ethnic groups in the US. However, little is known about spatio-temporal variations in HDP disparities. We used a Bayesian hierarchical regression approach to investigate spatio-temporal variations in HDP disparities from 2005 to 2014. County-level variation was firstly examined, followed by census tract-level variation assessment in counties where high HDP disparities were observed. A significant disadvantage in HDP was revealed for African Americans in Florida overall (Odds Ratio: 1.27, 95% Confidence Interval: 1.25, 1.29), with significant spatial variations. The greatest HDP disparities between African Americans and non-African Americans occurred in North Central Florida counties (the Big Bend region of Florida), with consistent patterns from 2005 to 2014. Analyses at census tract-level further revealed significant neighborhood disparities within these counties. Findings from this study provide important information for public health agencies and policymakers to reduce HDP disparities at the population level.
美国不同种族和族裔群体在妊娠高血压疾病(HDP)方面存在差异。然而,关于HDP差异的时空变化却知之甚少。我们采用贝叶斯分层回归方法来研究2005年至2014年期间HDP差异的时空变化。首先考察县级层面的变化,随后在观察到HDP差异较大的县进行普查区层面的变化评估。总体而言,佛罗里达州的非裔美国人在HDP方面存在显著劣势(优势比:1.27,95%置信区间:1.25,1.29),且存在显著的空间差异。非裔美国人和非非裔美国人之间最大的HDP差异出现在佛罗里达州中北部各县(佛罗里达州的大弯地区),2005年至2014年呈现出一致的模式。普查区层面的分析进一步揭示了这些县内显著的邻里差异。本研究的结果为公共卫生机构和政策制定者在人群层面减少HDP差异提供了重要信息。