Department of Otorhinolaryngology, KTO Karatay University Medical Faculty, Medicana Konya Hospital, Konya, Turkey.
Department of Otorhinolaryngology, KTO Karatay University Medical Faculty, Medicana Konya Hospital, Konya, Turkey.
Am J Otolaryngol. 2019 Sep-Oct;40(5):653-655. doi: 10.1016/j.amjoto.2019.05.021. Epub 2019 May 20.
This study aimed to compare if vertigo improved in patients when the dexamethasone used in the intratympanic (IT) injection was applied at body temperature or at room temperature.
The study included 54 patients who had undergone intratympanic treatment due to sudden hearing loss and tinnitus. The IT injection was administered to all patients, 2 times with 1-day intervals. Two different IT injection techniques were used for each patient: injecting dexamethasone at room temperature and injecting it at body temperature. Patients were asked to report the vertigo they felt immediately, and at 15 min after the injection using the visual analogue scale (VAS) and the four-point categorical rating scale (CRS-4).
The level of vertigo immediately after injection was lower when the dexamethasone was injected at body temperature rather that at room temperature for both the VAS and CRS-4 (p < 0.05). However, no statistical differences in the VAS and CRS-4 self-report values between the two methods were found 15 min after the injection (p > 0.05).
Vertigo due to IT decreases within minutes. When the IT drugs are administered at body temperature, temporal vertigo due to injection is lower than when they are administered at room temperature.
本研究旨在比较鼓室内（IT）注射地塞米松在体温或室温下应用时，患者的眩晕是否有所改善。
本研究纳入了 54 例因突发性听力损失和耳鸣而接受 IT 治疗的患者。所有患者均接受了 IT 注射，间隔 1 天进行 2 次注射。每位患者采用两种不同的 IT 注射技术：室温下注射地塞米松和体温下注射地塞米松。患者在注射后即刻和 15 分钟时使用视觉模拟量表（VAS）和四点分类评定量表（CRS-4）报告他们感到的眩晕。
VAS 和 CRS-4 均显示，体温下注射地塞米松后，即刻眩晕程度低于室温下注射（p<0.05）。然而，注射后 15 分钟时，两种方法的 VAS 和 CRS-4 自我报告值之间无统计学差异（p>0.05）。
IT 引起的眩晕在数分钟内即可缓解。当 IT 药物在体温下给药时，由于注射引起的短暂性眩晕低于室温下给药时。
