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本文引用的文献

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Complications and prognosis associated with intra-tympanic steroid injection to treat sudden sensorineural hearing impairment.鼓室内类固醇注射治疗突发性聋的并发症及预后。
Am J Otolaryngol. 2022 Jan-Feb;43(1):103221. doi: 10.1016/j.amjoto.2021.103221. Epub 2021 Sep 10.
3
Contemporary review of the causes and differential diagnosis of sudden sensorineural hearing loss.突发性聋病因及鉴别诊断的当代研究。
Int J Audiol. 2020 Apr;59(4):243-253. doi: 10.1080/14992027.2019.1689432. Epub 2019 Nov 12.
4
Comparison of the effects of the temperature of intratympanic dexamethasone injections on vertigo.鼓室内地塞米松注射温度对眩晕影响的比较。
Am J Otolaryngol. 2019 Sep-Oct;40(5):653-655. doi: 10.1016/j.amjoto.2019.05.021. Epub 2019 May 20.
5
Advances in Understanding, Diagnosis, and Treatment of Tinnitus.耳鸣的理解、诊断和治疗进展。
Adv Exp Med Biol. 2019;1130:109-128. doi: 10.1007/978-981-13-6123-4_7.
6
Contribution of intratympanic steroids in the primary treatment of sudden hearing loss.鼓室内注射类固醇在突发性听力损失初始治疗中的作用
Acta Otolaryngol. 2018 Jul;138(7):648-651. doi: 10.1080/00016489.2018.1438660. Epub 2018 Mar 7.
7
[Intratympanic injection therapy for therapy refractory acute hearing loss: A safe option for secondary treatment].鼓室内注射疗法治疗难治性急性听力损失:一种二级治疗的安全选择
HNO. 2015 Oct;63(10):698-700, 702-6. doi: 10.1007/s00106-015-0067-9.
8
Intratympanic corticosteroids injections: a systematic review of literature.鼓室内注射皮质类固醇:文献系统综述
Eur Arch Otorhinolaryngol. 2016 Sep;273(9):2271-8. doi: 10.1007/s00405-015-3689-3. Epub 2015 Jun 23.
9
Hyaluronic acid enhances gene delivery into the cochlea.透明质酸增强基因向耳蜗的传递。
Hum Gene Ther. 2012 Mar;23(3):302-10. doi: 10.1089/hum.2011.086. Epub 2012 Feb 8.
10
Sudden sensorineural hearing loss: a review of diagnosis, treatment, and prognosis.突发性感音神经性听力损失:诊断、治疗及预后综述
Trends Amplif. 2011 Sep;15(3):91-105. doi: 10.1177/1084713811408349. Epub 2011 May 22.

[鼓室内注射的耐受性与接受度]

[Tolerance and acceptance of intratympanic injections].

作者信息

Mühlmeier Guido, Tisch Matthias

机构信息

Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie, Bundeswehrkrankenhaus Ulm, Oberer Eselsberg 40, 89081, Ulm, Deutschland.

出版信息

HNO. 2022 Sep;70(9):685-690. doi: 10.1007/s00106-022-01202-9. Epub 2022 Aug 2.

DOI:10.1007/s00106-022-01202-9
PMID:35916897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9411221/
Abstract

BACKGROUND

Intratympanic steroids are a therapeutic component in sudden hearing loss related to cochlear affection. Little has been published on patients' acceptance and tolerance to date.

MATERIALS AND METHODS

A total of 84 patients were asked about health conditions and circumstances surrounding their intratympanic therapy.

RESULTS

The patients comprised 38 women and 46 men, aged 57.2 years on average, who had mostly been referred by their ENT physician for second-line treatment. Reported were injection pain by 3.6%, discomfort by 22.6%, tolerability by 67.9%, and painlessness by 41.7% (more than one answer possible). Whereas 77.4% recommended intratympanic treatment, reasons for no recommendation were lack of efficacy and an unpleasant sensation.

CONCLUSION

The majority of patients rated intratympanic therapy as bearable and recommendable. Close patient guidance seems to be an important part of the treatment.

摘要

背景

鼓室内注射类固醇是与耳蜗病变相关的突发性听力损失的一种治疗手段。迄今为止,关于患者的接受度和耐受性的报道较少。

材料与方法

共询问了84例患者关于其鼓室内治疗的健康状况及相关情况。

结果

患者包括38名女性和46名男性,平均年龄57.2岁,大多由耳鼻喉科医生转诊进行二线治疗。报告的注射疼痛发生率为3.6%,不适发生率为22.6%,耐受性发生率为67.9%,无痛发生率为41.7%(可能有多个答案)。77.4%的患者推荐鼓室内治疗,不推荐的原因是缺乏疗效和感觉不适。

结论

大多数患者认为鼓室内治疗是可耐受且值得推荐的。密切的患者指导似乎是治疗的重要组成部分。