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[铜绿假单胞菌:致病性、预防与治疗方法]

[Pseudomonas aeruginosa: pathogenicity, prevention and therapeutic approaches].

作者信息

Kujath P, Hügelschäffer C

出版信息

Zentralbl Chir. 1987;112(9):558-63.

PMID:3113091
Abstract

Pseudomonas aeruginosa has proved to be a dangerous nosocomial pathogen is growing importance. Its pathogenicity is attributable to its great variety of toxic mechanisms which are capable of attacking all parts of the organism, primarily organs with impaired resistance. Antibiotics had been found to yield little lasting success. Therefore, an attempt was made to apply to 30 patients three-per-cent boric acid to cope with locally delimited Pseudomonas wound infections. Therapy could be completed with good success in less than six days on average. Only germ reduction was achievable on three patients with chronic osteomyelitis. Toxic side-effects were not recordable.

摘要

铜绿假单胞菌已被证明是一种日益重要的危险医院病原体。其致病性归因于多种毒性机制,这些机制能够攻击机体的各个部位,主要是抵抗力受损的器官。已发现抗生素几乎没有持久的疗效。因此,尝试对30名患者应用3%的硼酸来应对局部局限的铜绿假单胞菌伤口感染。平均不到六天就能成功完成治疗。对于三名慢性骨髓炎患者,仅实现了细菌数量减少。未记录到毒性副作用。

相似文献

1
[Pseudomonas aeruginosa: pathogenicity, prevention and therapeutic approaches].[铜绿假单胞菌:致病性、预防与治疗方法]
Zentralbl Chir. 1987;112(9):558-63.
2
Prospects for the next anti-Pseudomonas drug.下一代抗假单胞菌药物的前景。
Curr Opin Pharmacol. 2009 Oct;9(5):558-65. doi: 10.1016/j.coph.2009.08.006. Epub 2009 Sep 12.
3
[Antibiotic, triphenylmethane dyes and boric acid in increased occurrence of Pseudomonas aeruginosa].[抗生素、三苯甲烷染料和硼酸与铜绿假单胞菌发生率增加的关系]
Z Haut Geschlechtskr. 1970 Apr 15;45(8):329-32.
4
[Pseudomonas aeruginosa sensitivity to boric acid, carbenicillin and deposul and their potential use in treating Pseudomonas aeruginosa infection].[铜绿假单胞菌对硼酸、羧苄青霉素和去甲万古霉素的敏感性及其在治疗铜绿假单胞菌感染中的潜在用途]
Mikrobiol Zh (1978). 1981 May-Jun;43(3):369-72.
5
[Does a rational therapeutic plan exist for nosocomial bacteremia caused by Pseudomonas aeruginosa?].对于铜绿假单胞菌引起的医院获得性菌血症是否存在合理的治疗方案?
Med Clin (Barc). 1987 Oct 24;89(13):572.
6
Treatment of Pseudomonas aeruginosa infection.
Br J Hosp Med. 1984 Feb;31(2):136-40.
7
Mandibular osteomyelitis due to Pseudomonas aeruginosa. Case report.铜绿假单胞菌所致下颌骨骨髓炎。病例报告。
Minerva Stomatol. 2008 Jun;57(6):323-9.
8
Current therapies for pseudomonas aeruginosa.铜绿假单胞菌的当前治疗方法。
Crit Care Clin. 2008 Apr;24(2):261-78, viii. doi: 10.1016/j.ccc.2007.12.004.
9
Emergence of highly antibiotic-resistant Pseudomonas aeruginosa in relation to duration of empirical antipseudomonal antibiotic treatment.与经验性抗铜绿假单胞菌抗生素治疗持续时间相关的高度耐药铜绿假单胞菌的出现
Clin Perform Qual Health Care. 1999 Apr-Jun;7(2):83-7.
10
Resistance pattern and antibiotic therapy in surgery: experience in a German hospital 1981/83.外科手术中的耐药模式与抗生素治疗:1981/83年德国一家医院的经验
Scand J Gastroenterol Suppl. 1984;100:53-60.

引用本文的文献

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Citric Acid as an Alternative to Boric Acid in the Treatment of Chronic Suppurative Otitis Media.柠檬酸作为硼酸的替代物用于慢性化脓性中耳炎的治疗
Korean J Fam Med. 2019 Jul;40(4):278-279. doi: 10.4082/kjfm.18.0017. Epub 2018 Jul 27.
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Acetic acid dressings: Finding the Holy Grail for infected wound management.醋酸敷料:寻找感染伤口管理的圣杯。
Indian J Plast Surg. 2017 Sep-Dec;50(3):273-280. doi: 10.4103/ijps.IJPS_245_16.
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Assessment of the effectiveness of silver-coated dressing, chlorhexidine acetate (0.5%), citric acid (3%), and silver sulfadiazine (1%) for topical antibacterial effects against the multi-drug resistant Pseudomonas aeruginosa infecting full-skin thickness burn wounds on rats.
评估涂银敷料、0.5%醋酸氯己定、3%柠檬酸和1%磺胺嘧啶银对感染大鼠全层皮肤烧伤创面的多重耐药铜绿假单胞菌的局部抗菌效果。
Int Surg. 2013 Oct-Dec;98(4):416-23. doi: 10.9738/INTSURG-D-13-00017.1.
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Simple and effective approach for the treatment of traumatic wounds in non-diabetic patients: a prospective open study.一种用于非糖尿病患者创伤性伤口治疗的简单有效方法:一项前瞻性开放性研究。
Int Wound J. 2013 Oct;10(5):585-9. doi: 10.1111/j.1742-481X.2012.01026.x. Epub 2012 Jul 11.