Kofoed H, Svalastoga E, Grønlund J
Acta Physiol Hung. 1987;69(2):239-44.
The influence of arterial hypoxia on bone marrow pressure, regional blood flow and oxygen and carbon dioxide tensions was investigated by simultaneous and continuous measurements in the femoral condyles of 8 rabbits. Arterial hypoxia was obtained by hypoventilation. The subchondral gas tensions and regional blood flow were measured by a previously described technique based on mass spectrometry. Arterial hypoxia caused a significant decrease in subchondral oxygen tension and an increase in subchondral carbon dioxide tension. There was no significant change in bone marrow pressure and regional blood flow.
通过对8只家兔股骨髁进行同步连续测量，研究了动脉性低氧对骨髓压力、局部血流量以及氧和二氧化碳张力的影响。通过通气不足造成动脉性低氧。采用一种基于质谱分析的先前描述的技术测量软骨下气体张力和局部血流量。动脉性低氧导致软骨下氧张力显著降低，软骨下二氧化碳张力升高。骨髓压力和局部血流量无显著变化。
