Department of Health Sciences, Public University of Navarra, Pamplona, Navarra, Spain; Navarrabiomed, IdiSNA, Navarra Institute for Health Research, Pamplona, Navarra, Spain; CIBER of Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.
Department of Health Sciences, Public University of Navarra, Pamplona, Navarra, Spain; Navarrabiomed, IdiSNA, Navarra Institute for Health Research, Pamplona, Navarra, Spain; CIBER of Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain; Geriatric Department, Complejo Hospitalario de Navarra (CHN), Pamplona, Navarra, Spain.
J Am Med Dir Assoc. 2019 Jul;20(7):866-873. doi: 10.1016/j.jamda.2019.04.001. Epub 2019 May 24.
To evaluate the effects of an exercise intervention on physical function, maximal muscle strength, and muscle power in very old hospitalized patients.
In a randomized controlled trial, 130 hospitalized patients were allocated to an exercise intervention (n = 65) or a control group (n = 65). The intervention consisted of a multicomponent exercise training program performed during 5-7 consecutive days (2 sessions/d). The usual care group received habitual hospital care, which included physical rehabilitation when needed.
Acute care for elderly unit. Older adults age >75 years.
Physical function, assessed with the Short Physical Performance Battery test and the Gait Velocity Test (GVT), were the primary endpoints. The GVT was also administered under dual-task conditions (ie, verbal and arithmetic GVT). The functional tasks were recorded using an inertial sensor unit to determine the movement pattern. The secondary endpoints were maximal muscle strength and muscle power output.
The exercise intervention program provided significant benefits over usual care. At discharge (primary time point), the exercise group showed a mean increase of 1.7 points in the Short Physical Performance Battery scale (95% confidence interval [CI] 0.98, 2.42) and 0.14 m·s-1 in the GVT (95% CI 0.086, 0.194) over the usual care group. The intervention also improved the verbal (0.151; 95% CI 0.119, 0.184 vs -0.001; 95% CI -0.025, 0.033 in the control group) and arithmetic GVT (0.115; 95% CI 0.077, 0.153 vs -0.004; 95% CI -0.044, 0.035). Significant benefits were also observed in the intervention group in movement pattern, as well as in muscle strength and muscle power.
An individualized multicomponent exercise training program improves physical function, maximal muscle strength, and muscle power in acutely hospitalized older patients. These findings support the importance of physical exercise for avoiding the loss of physical functional capacity that frequently occurs during hospitalization in older adults.
评估一项运动干预对非常年老的住院患者身体功能、最大肌肉力量和肌肉力量的影响。
在一项随机对照试验中，将 130 名住院患者分配到运动干预组（n=65）或对照组（n=65）。干预措施包括在连续 5-7 天内进行多组分运动训练方案（每天 2 次）。常规护理组接受常规医院护理，包括在需要时进行身体康复。
老年人急症护理病房。年龄>75 岁的老年人。
身体功能，通过短体适能测试和步态速度测试（GVT）进行评估，是主要终点。GVT 还在双重任务条件下（即言语和算术 GVT）进行测试。使用惯性传感器单元记录功能任务，以确定运动模式。次要终点为最大肌肉力量和肌肉功率输出。
运动干预方案优于常规护理。在出院时（主要时间点），运动组在短体适能测试量表上的平均得分增加了 1.7 分（95%置信区间[CI] 0.98，2.42），在 GVT 中增加了 0.14 m·s-1（95% CI 0.086，0.194）常规护理组。该干预措施还改善了言语 GVT（0.151；95% CI 0.119，0.184 与-0.001；95% CI -0.025，0.033 在对照组）和算术 GVT（0.115；95% CI 0.077，0.153 与-0.004；95% CI -0.044，0.035）。运动组在运动模式以及肌肉力量和肌肉功率方面也观察到了显著的益处。
个体化的多组分运动训练方案可改善急性住院老年患者的身体功能、最大肌肉力量和肌肉力量。这些发现支持了体育锻炼对于避免老年人住院期间经常发生的身体功能能力丧失的重要性。
