Senellart F, Normand J, Bozio A, André M, Sassolas F, Jocteur-Monrozier D, Champsaur G
Arch Mal Coeur Vaiss. 1987 Apr;80(4):530-6.
This study takes stock of the current results of physiological correction (Mustard's or Senning's operation) in simple transposition of the great vessels, at a time when anatomical corrections, or detranspositions, are developing. Between January 1, 1974 and December 31, 1984, 168 neonates with simple transposition of the great vessels were operated upon and followed up for a mean period of 3.67 years (up to 11 years and 10 months). Thirty of them died before correction (12.7% mortality rate with palliative surgery) and 15 immediately after corrective surgery (11.2%). Among the 111 children who survived corrective surgery, the results were satisfactory in 62.7%, fair in 17.8% and poor in 10.2%; the late mortality rate was 9.3%. Post-correction morbidity mainly consisted of mechanical complications suspected in one-third of the patients (with 3 consecutive deaths) and heart rhythm disorders (50% of patients in this series had abnormal Holter recordings), with predominance of atrial rhythm disorders (regression of sinus rhythm was 3.82% per annum). This, after correction the survival curve underwent an actuarial regression of 1.31% per annum. This primary and secondary morbidity and mortality justifies a switch to anatomical corrections the results of which remain to be fully evaluated.
本研究对大动脉完全转位的生理矫正(Mustard手术或Senning手术)的当前结果进行了评估,此时解剖矫正或去转位手术正在发展。在1974年1月1日至1984年12月31日期间,对168例大动脉完全转位的新生儿进行了手术,并进行了平均3.67年(最长11年10个月)的随访。其中30例在矫正前死亡(姑息手术死亡率为12.7%),15例在矫正手术后立即死亡(11.2%)。在111例矫正手术后存活的儿童中,结果满意的占62.7%,中等的占17.8%,差的占10.2%;晚期死亡率为9.3%。矫正后的发病率主要包括三分之一患者疑似出现的机械并发症(有3例连续死亡)和心律失常(本系列中50%的患者动态心电图记录异常),以房性心律失常为主(窦性心律的回归率为每年3.82%)。据此,矫正后生存曲线的精算回归率为每年1.31%。这种原发性和继发性的发病率和死亡率证明转向解剖矫正手术是合理的,其结果仍有待全面评估。