Gunge M, Yamamoto H
Arch Otorhinolaryngol. 1987;244(1):30-5. doi: 10.1007/BF00453488.
To date, 96 cases of central hemangiomas of the jawbones have been described in the literature. Of these cases, the mandible has been more affected than the maxilla, while approximately 50% of all cases occur in the first and second decades of life. Histopathologically, cavernous and capillary types are often found, in contrast to the central venous type, which is rare. We have recently treated a 44-year-old man, who was found to have a central venous hemangioma in his mandible. Immunohistochemical studies were performed using factor-VIII-related antigen as well as various lectins as markers for tumor endothelial cells. Our results showed that four kinds of lectins (UEA-I, PNA, ConA, and DBA) were useful for the marker as factor-VIII-related antigen. Scanning electron microscopic findings of this tumor demonstrated that the lumina of the blood vessels were more rough, while the lining endothelial cells were more irregular when compared with those of the normal vascular system.
迄今为止，文献中已报道了96例颌骨中央血管瘤病例。在这些病例中，下颌骨比上颌骨受累更多，约50%的病例发生在生命的第一个和第二个十年。组织病理学上，常发现海绵状和毛细血管型，而中央静脉型罕见。我们最近治疗了一名44岁男性，他被发现下颌骨有中央静脉血管瘤。使用因子VIII相关抗原以及各种凝集素作为肿瘤内皮细胞的标志物进行了免疫组织化学研究。我们的结果表明，四种凝集素（UEA-I、PNA、ConA和DBA）作为因子VIII相关抗原的标志物很有用。该肿瘤的扫描电子显微镜检查结果表明，与正常血管系统相比，血管腔更粗糙，内衬内皮细胞更不规则。
