Department of the Graduate School, Tianjin Medical University, Tianjin, PR China.
Department of General Surgery, Tianjin Children's Hospital, Tianjin, PR China.
J Comp Eff Res. 2019 Jul;8(10):767-780. doi: 10.2217/cer-2019-0036. Epub 2019 May 29.
We aimed to compare conservative treatment with surgery for uncomplicated pediatric appendicitis to estimate effectiveness and safety. Data recorded until September 2018 were searched, and relevant academic articles from PubMed, EMBASE, the Cochrane Library and other libraries were selected. STATA version 13.0 (Stata Corporation, TX, USA) was used for statistical analysis. We identified nine eligible papers. The study reported a significant difference in the success rate of treatment in 1 month and in 1 year, and no difference in the incidence of complications. The patients with fecaliths showed low treatment efficacy in conservative treatment group (p < 0.05). Standardized conservative treatment as inpatients for pediatric appendicitis is safe and feasible. Appendectomy was the better choice for patients with fecaliths.
我们旨在比较单纯性小儿阑尾炎的保守治疗与手术治疗，以评估其疗效和安全性。检索截至 2018 年 9 月的数据，并选择来自 PubMed、EMBASE、Cochrane 图书馆和其他图书馆的相关学术文章。使用 STATA 版本 13.0（Stata Corporation，TX，USA）进行统计分析。我们确定了 9 篇符合条件的论文。研究报告显示，在 1 个月和 1 年内的治疗成功率存在显著差异，且并发症发生率无差异。粪石患者在保守治疗组的治疗效果较低（p<0.05）。对小儿阑尾炎进行标准化的住院保守治疗是安全可行的。对于有粪石的患者，阑尾切除术是更好的选择。
