Visagan Ravindran, Hall Andrew, Bradford Robert, Khalil Sherif, Saeed Shakeel Riaz
Skull Base Unit, National Hospital for Neurology & Neurosurgery, Queen Square, London, United Kingdom.
Royal National Throat Nose and Ear Hospital, Gray's Inn Road, London, United Kingdom.
J Neurol Surg B Skull Base. 2019 Jun;80(3):310-315. doi: 10.1055/s-0038-1668541. Epub 2018 Sep 25.
To date, no European study has compared approach-specific outcome data in vestibular schwannoma (VS) surgery stratified by tumor size. We analyzed hospital length of stay (LOS), intensive therapy/high-dependency unit (ITU/HDU) LOS, and complications in patients undergoing VS surgery via the translabyrinthine (TL) versus retrosigmoid (RS) approaches, stratifying for tumor size. Prospective database undergoing retrospective review. Tertiary center. A total of 117 patients with VS undergoing TL ( = 71) or RS ( = 46) surgical resection from 2011 to 2016 were analyzed. Data including age, gender, surgical approach, tumor size, hospital, and ITU/HDU LOS and postoperative complications were evaluated. Therapeutic-VS surgery via either TL or RS approach. LOS (hospital/intensive care unit). Hospital LOS was significantly greater in patients undergoing the RS approach versus TL approach in VS between 31 and 40 mm (11 versus 7 days, < 0.0006). The mean ITU/HDU LOS was greater in the RS group compared with the TL group (4.6 versus 1, > 0.05). Reported complications were higher in the RS group ( = 40 versus 22). A post hoc analysis of the 31 to 40 mm group revealed no statistically significant difference in the American Society of Anesthesiologists grade or preoperative performance status. In our practice, in VS sized 31 to 40 mm patients stay 4 days longer post RS compared with TL surgery. This translates to £1600 extra per patient in the UK. Our data may inform decision-making during the skull base multidisciplinary team and the consent process to help decide the ideal operative approach for the patient.
迄今为止,尚无欧洲研究对按肿瘤大小分层的前庭神经鞘瘤(VS)手术中特定入路的结局数据进行比较。我们分析了经迷路(TL)与乙状窦后(RS)入路进行VS手术患者的住院时间(LOS)、重症治疗/高依赖病房(ITU/HDU)住院时间以及并发症情况,并按肿瘤大小进行分层。 对前瞻性数据库进行回顾性分析。 三级中心。 分析了2011年至2016年期间共117例行TL(n = 71)或RS(n = 46)手术切除的VS患者。评估了包括年龄、性别、手术入路、肿瘤大小、医院以及ITU/HDU住院时间和术后并发症等数据。 治疗方法——通过TL或RS入路进行VS手术。 住院时间(医院/重症监护病房)。 在肿瘤大小为31至40毫米的VS患者中,采用RS入路的患者住院时间显著长于采用TL入路者(11天对7天,P < 0.0006)。RS组的平均ITU/HDU住院时间长于TL组(4.6天对1天,P>0.05)。RS组报告的并发症更多(40例对22例)。对31至40毫米组的事后分析显示,美国麻醉医师协会分级或术前功能状态无统计学显著差异。 在我们的实践中,对于肿瘤大小为31至40毫米的VS患者,与TL手术相比,RS手术后住院时间长4天。在英国,这相当于每位患者额外花费1600英镑。我们的数据可为颅底多学科团队决策和知情同意过程提供参考,以帮助为患者确定理想的手术入路。