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乙状窦后入路与迷路后入路切除前庭神经鞘瘤的发病率

Morbidity Rate of the Retrosigmoid versus Translabyrinthine Approach for Vestibular Schwannoma Resection.

作者信息

Obaid Sami, Nikolaidis Ioannis, Alzahrani Musaed, Moumdjian Robert, Saliba Issam

机构信息

Division of Neurosurgery, Head and Neck Surgery, Department of Surgery, Montreal University Hospital Center (CHUM), Montreal, Canada.

Division of Otolaryngology, Head and Neck Surgery, Department of Surgery, Montreal University Hospital Center (CHUM), Montreal, Canada.

出版信息

J Audiol Otol. 2018 Oct;22(4):236-243. doi: 10.7874/jao.2018.00164. Epub 2018 Aug 22.

Abstract

BACKGROUND AND OBJECTIVES

Controversy related to the choice of surgical approach for vestibular schwannoma (VS) resection remains. Whether the retrosigmoid (RS) or translabyrinthine (TL) approach should be performed is a matter of debate. In the context of a lack of clear evidence favoring one approach, we conducted a retrospective study to compare the morbidity rate of both surgical approaches. Subjects and.

METHODS

168 patients underwent surgical treatment (2007-2013) for VS at our tertiary care center. There were no exclusion criteria. Patients were separated into two groups according to the surgical approach: TL group and RS group. Signs and symptoms including ataxia, headache, tinnitus, vertigo and cranial nerve injuries were recorded pre- and postoperatively. Surgical complications were analyzed. Perioperative facial nerve function was measured according to House-Brackmann grading system.

RESULTS

Tumor resection was similar in both groups. Facial paresis was significantly greater in RS group patients preoperatively, in the immediate postoperative period and at one year follow-up (p<0.05). A constant difference was found between both groups at all three periods (p=0.016). The evolution of proportion was not found to be different between both groups (p=0.942), revealing a similar rate of surgically related facial paresis. Higher rate of ataxic gait (p=0.019), tinnitus (p=0.039) and cranial nerve injuries (p=0.016) was found in RS group patients. The incidence of headache, vertigo, vascular complications, cerebrospinal fluid leak and meningitis was similar in both groups. No reported mortality in this series.

CONCLUSIONS

Both approaches seem similar in terms of resection efficacy. However, according to our analysis, the TL approach is less morbid. Thus, for VS in which hearing preservation is not considered, TL approach is preferable.

摘要

背景与目的

关于前庭神经鞘瘤(VS)切除术手术入路的选择仍存在争议。应采用乙状窦后(RS)入路还是经迷路(TL)入路一直是个有争议的问题。在缺乏明确证据支持某一种入路的情况下,我们进行了一项回顾性研究以比较两种手术入路的发病率。对象与……

方法

168例患者于2007年至2013年在我们的三级医疗中心接受VS手术治疗。无排除标准。根据手术入路将患者分为两组:TL组和RS组。记录术前和术后包括共济失调、头痛、耳鸣、眩晕和颅神经损伤在内的体征和症状。分析手术并发症。根据House - Brackmann分级系统测量围手术期面神经功能。

结果

两组的肿瘤切除情况相似。RS组患者术前、术后即刻及随访一年时的面部轻瘫明显更严重(p<0.05)。在所有三个时期两组之间均发现有持续差异(p = 0.016)。两组之间比例的变化未发现有差异(p = 0.942),表明手术相关面部轻瘫的发生率相似。RS组患者共济失调步态(p = 0.019)、耳鸣(p = 0.039)和颅神经损伤(p = 0.016)的发生率更高。两组头痛、眩晕、血管并发症、脑脊液漏和脑膜炎的发生率相似。本系列中无死亡报告。

结论

两种入路在切除效果方面似乎相似。然而,根据我们的分析,TL入路的发病率较低。因此,对于不考虑保留听力的VS,TL入路更可取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d56c/6233933/94b38a450b25/jao-2018-00164f1.jpg

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