Centre for Heart Lung Innovation, Providence Healthcare Research Institute, The University of British Columbia, St. Paul's Hospital.
Department of Physical Therapy.
Curr Opin Support Palliat Care. 2019 Sep;13(3):174-178. doi: 10.1097/SPC.0000000000000434.
This article presents a summary of the evidence relating to supplemental oxygen use for the management of dyspnea in patients with interstitial lung disease (ILD).
In contrast to the majority of the available literature, recent findings suggest that supplemental oxygen can significantly reduce exertional dyspnea in ILD. ILD patients' need for supplemental oxygen often surpasses the levels that the most commonly used oxygen delivery systems provide. More effective delivery of supplemental oxygen has the potential for greater relief of dyspnea. There is also evidence suggesting that indications for supplemental oxygen may differ in ILD compared with other chronic lung diseases.
Large clinical trials are needed to determine if the reductions in dyspnea with supplemental oxygen observed in the laboratory setting can translate into meaningful benefits in everyday life for patients with ILD. More effective and practical oxygen delivery systems are needed. Future guidelines should consider including recommendations addressing the potential role of supplemental oxygen for mildly hypoxemic patients with ILD as well as recommendations specific to supplemental oxygen use for exercise training in ILD.
本文总结了有关补充氧气治疗间质性肺疾病（ILD）患者呼吸困难的证据。
与大多数现有文献相反，最近的研究结果表明，补充氧气可以显著减轻ILD 患者的运动性呼吸困难。ILD 患者对补充氧气的需求往往超过了最常用的供氧系统所能提供的水平。更有效地输送补充氧气有可能更大程度地缓解呼吸困难。也有证据表明，与其他慢性肺部疾病相比，ILD 患者补充氧气的适应证可能有所不同。
需要进行大型临床试验来确定在实验室环境中观察到的补充氧气对呼吸困难的缓解是否能为ILD 患者的日常生活带来有意义的益处。需要更有效和实用的供氧系统。未来的指南应考虑包括针对轻度低氧血症的ILD 患者补充氧气的潜在作用的建议，以及ILD 患者运动训练中补充氧气使用的具体建议。
