比较了电休克治疗（ECT）和促甲状腺激素释放激素（TRH）引起的催乳素释放模式。

The patterns of prolactin release by ECT and TRH compared.

作者信息

Markianos M, Papakostas Y, Stefanis C

出版信息

Life Sci. 1987 Sep 7;41(10):1273-6. doi: 10.1016/0024-3205(87)90206-2.

DOI:10.1016/0024-3205(87)90206-2

Abstract

The patterns of prolactin release after bilateral ECT and after 0.4 mg TRH i.v. were studied in 11 female melancholic patients in a 5-min sampling protocol. Mean prolactin peaking times were 10.2 min after ECT and 20.5 min after TRH. The elimination rate coefficients were significantly lower--and the corresponding half-lives longer--for prolactin released by TRH than by ECT. A significant positive correlation of the maximal prolactin responses by the two stimuli was also found.

摘要

在一项5分钟采样方案中，对11名女性忧郁症患者进行了双侧电休克治疗（ECT）后及静脉注射0.4毫克促甲状腺激素释放激素（TRH）后催乳素释放模式的研究。ECT后催乳素平均峰值时间为10.2分钟，TRH后为20.5分钟。TRH释放的催乳素的消除速率系数显著更低，相应的半衰期更长。还发现两种刺激引起的最大催乳素反应之间存在显著正相关。

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