十四醛作为细菌生物发光中天然醛的证据。
Evidence for tetradecanal as the natural aldehyde in bacterial bioluminescence.
作者信息
Ulitzur S, Hastings J W
出版信息
Proc Natl Acad Sci U S A. 1979 Jan;76(1):265-7. doi: 10.1073/pnas.76.1.265.
Abstract
Dim aldehyde mutants of the luminous bacterium Beneckea harveyi emit light with exogenously added long-chain aliphatic aldehyde. In one class of these mutants, luminescence is also stimulated by myristic (tetradecanoic) acid. In such mutants the amount of light obtained by the addition of a small (limiting) amount of either tetradecanal or myristic acid may be increased 60-fold by cyanide and other agents that block respiration. This indicates that the fatty acid product of the luminescent reaction is recycled. The effect, like the stimulation by exogenous fatty acid, exhibits specificity for the 14-carbon compound, suggesting that tetradecanal is the natural aldehyde. In those aldehyde mutants that are not stimulated to emit light by fatty acids, and thus presumably lack the recycling system, the chain-length-specific stimulation by cyanide does not occur.
摘要
哈维氏贝内克氏发光菌的二醛突变体在外源添加长链脂肪醛时会发光。在这类突变体的一个类别中，肉豆蔻酸（十四烷酸）也能刺激发光。在这些突变体中，添加少量（限量）十四醛或肉豆蔻酸所产生的光量，可因氰化物和其他阻断呼吸作用的试剂而增加60倍。这表明发光反应的脂肪酸产物会被循环利用。这种效应，如同外源脂肪酸的刺激作用一样，对含14个碳的化合物具有特异性，这表明十四醛是天然醛。在那些不会被脂肪酸刺激发光、因此可能缺乏循环系统的醛突变体中，不会出现氰化物对链长的特异性刺激作用。
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