Ufoaroh Chinyelu Uchenna, Ele Prince Udegbunam, Anyabolu Arthur Ebelenna, Enemuo Emeka Hyacinth, Emegoakor Chiemelu Dickson, Okoli Chinedu Christian, Umeh Eric Okechukwu, Anyabolu Ernest Ndukaife
Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Medicine.
Nnamdi Azikiwe University Teaching Hospital, Nnewi, Medicine.
Afr Health Sci. 2019 Mar;19(1):1745-1756. doi: 10.4314/ahs.v19i1.51.
Post-operative pulmonary complications (PPCs) are recurring causes of rising morbidity and mortality in surgeries. This study sought to evaluate pre-operative risk factors for PPCs in abdominal surgerypatients in Nigeria.
This was a prospective study in patients booked for surgery in 2014. Biodata, medical his tory, pre-operative respiratory and cardiovascular examination findings, body mass index, serum albumin, serum urea, ventilatory function, chest x-rays and oxygen saturation were obtained. The association between pre-operative variables and PPCs was determined.
The pre-operative spirometry was predominantly restrictive (62%). Overall, the prevalence of PPCs was 52%. This included non-productive cough (14%), isolated productive cough (10%), productive cough with abnormal chest finding (16%), pneumonia (8%), pleural effusion (5%), ARDS (2%). Percentage predicted FEV1 and FVC were lower in participants with PPCs. (p= 0.03 and p=0.01respectively). Pre-operative cough, shortness of breath and consolidation were associated with PPCs (p< 0.05). Post-operative respiratory rate and pulse rate in participants with PPCs were higher than the values in those without PPCs (p=0.03 and p=0.05).
The prevalence of PPCs was high in this study. Pre-operative cough, shortness of breath, consolidation, abnormally low percentage predicted FEV1 and FVC were associated with PPCs.
术后肺部并发症(PPCs)是手术中发病率和死亡率不断上升的反复出现的原因。本研究旨在评估尼日利亚腹部手术患者发生PPCs的术前危险因素。
这是一项针对2014年预定手术患者的前瞻性研究。收集了患者的生物数据、病史、术前呼吸和心血管检查结果、体重指数、血清白蛋白、血清尿素、通气功能、胸部X光片和血氧饱和度。确定术前变量与PPCs之间的关联。
术前肺活量测定主要为限制性通气(62%)。总体而言,PPCs的患病率为52%。这包括干咳(14%)、单纯咳痰(10%)、有胸部异常表现的咳痰(16%)、肺炎(8%)、胸腔积液(5%)、急性呼吸窘迫综合征(2%)。发生PPCs的参与者预测的第一秒用力呼气容积(FEV1)和用力肺活量(FVC)百分比更低(分别为p=0.03和p=0.01)。术前咳嗽、呼吸急促和实变与PPCs相关(p<0.05)。发生PPCs的参与者术后呼吸频率和脉搏率高于未发生PPCs的参与者(p=0.03和p=0.05)。
本研究中PPCs的患病率较高。术前咳嗽、呼吸急促、实变、预测的FEV1和FVC百分比异常低与PPCs相关。