Miyake T, Uhara H, Ishii N, Okuyama R
1Department of Dermatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621 Japan.
2Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Int Cancer Conf J. 2017 Apr 9;6(3):135-137. doi: 10.1007/s13691-017-0292-z. eCollection 2017 Jul.
We report the case of a 71-year-old Japanese man with squamous cell carcinoma arising from lupus vulgaris on the face, >60 years after the appearance of the lupus vulgaris. The red plaque on the patient's face had been diagnosed as a hemangioma or rosacea at several hospitals, although he had had lung tuberculosis at the age of 4 and his father died from lung tuberculosis at 38 years of age. Although lupus vulgaris was the most frequent clinical form of true skin tuberculosis until the 1960s, it has become rare since then. Malignant tumors are known to occur in individuals with lupus vulgaris, with a reported rate of 0.5-10.5%. In light of Japan's "graying society," tuberculosis is still an important disorder, and clinicians must remain aware of cutaneous tuberculosis.
我们报告了一例71岁的日本男性病例，其面部寻常狼疮出现60多年后发生了鳞状细胞癌。尽管该患者4岁时患过肺结核，其父亲38岁死于肺结核，但他面部的红色斑块在几家医院被诊断为血管瘤或酒渣鼻。直到20世纪60年代，寻常狼疮都是真性皮肤结核最常见的临床类型，但此后已变得罕见。已知寻常狼疮患者会发生恶性肿瘤，报告发生率为0.5%-10.5%。鉴于日本的“老龄化社会”，结核病仍然是一种重要疾病，临床医生必须始终警惕皮肤结核。
