Khudgarian M V, Megrabian A A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1987;87(6):863-6.
Using acridine orange fluorochrome staining of fixed smears of peripheral blood the authors have investigated the lymphocyte functional activity in epileptic patients receiving the conventional anticonvulsive therapy including lithium carbonate. It has been established that the dynamics of the functional activity of lymphocytes in epileptic patients show no direct relationship with the therapeutic effect. Cytochemical parameters of the lymphocyte functional activity change in parallel with the clinical picture of the disease under the impact of treatment, i.e., they are directly correlated with the clinical pattern.
作者采用吖啶橙荧光染色法对接受包括碳酸锂在内的传统抗惊厥治疗的癫痫患者外周血固定涂片进行检测，以研究其淋巴细胞功能活性。结果发现，癫痫患者淋巴细胞功能活性的动态变化与治疗效果无直接关系。在治疗影响下，淋巴细胞功能活性的细胞化学参数变化与疾病临床表现平行，即它们与临床症状直接相关。
