结合还是水解？独脚金内酯受体如何工作？
Binding or Hydrolysis? How Does the Strigolactone Receptor Work?
机构信息
Department of Genetics, Faculty of Biology and Environmental Protection, University of Silesia, Katowice 40-032, Poland.
ARC Centre of Excellence in Plant Energy Biology, School of Agriculture, Food and Wine, The University of Adelaide, Glen Osmond, SA 5064, Australia.
出版信息
Trends Plant Sci. 2019 Jul;24(7):571-574. doi: 10.1016/j.tplants.2019.05.001. Epub 2019 May 28.
The strigolactone (SL) receptor in plants is unusual in that it both binds and hydrolyses SL molecules. Landmark studies had proposed that a product of hydrolysis irreversibly binds the receptor and then activates signalling. However, recent breakthrough articles (Seto et al. Nat. Commun. 2019;10:191 and Shabek et al. Nature 2018;563:652-656) have revealed a new model based on inhibition of hydrolysis by protein conformation.
在植物中，独脚金内酯（SL）受体很特别，因为它既能结合又能水解 SL 分子。具有里程碑意义的研究曾提出，水解的产物不可逆地结合受体，然后激活信号转导。然而，最近的突破性文章（Seto 等人，《自然通讯》2019；10：191 和 Shabek 等人，《自然》2018；563：652-656）揭示了一个基于蛋白构象抑制水解的新模型。
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