Chan P, Vincent J W, Wangemann R T
Arch Dermatol. 1987 Aug;123(8):1042-5.
Healing time, infection rate, and residual scar formation were compared in carbon dioxide laser burns in rats treated in four ways: Spandra composite dressing, OpSite composite dressing, Petrolatum Gauze (USP), and no treatment. There were no infections and no differences in scar formation among the treatment groups. The mean healing times were ten days for the polyurethane dressings (Spandra and OpSite), 13 days for Petrolatum Gauze, and 16 days for the untreated group. Spandra was easier to apply and handle than OpSite. These findings suggest that synthetic gas-permeable dressings promote healing after cutaneous carbon dioxide laser surgery more effectively than conventional treatments of ointment-impregnated gauze or leaving the wound exposed to the air.
对采用四种方式治疗的大鼠二氧化碳激光烧伤的愈合时间、感染率和残余瘢痕形成情况进行了比较：使用斯潘德拉复合敷料、 Opsite复合敷料、凡士林纱布（美国药典标准），以及不进行治疗。各治疗组均未发生感染，瘢痕形成也无差异。聚氨酯敷料（斯潘德拉和Opsite）的平均愈合时间为10天，凡士林纱布为13天，未治疗组为16天。斯潘德拉比Opsite更易于应用和操作。这些发现表明，合成透气敷料比传统的浸渍软膏纱布治疗或让伤口暴露于空气中能更有效地促进皮肤二氧化碳激光手术后的愈合。
