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[A case of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) with the largest lesion in the temporal lobe].
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Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) with intracranial Epstein-Barr virus infection: A Case Report.伴有颅内爱泼斯坦-巴尔病毒感染的类固醇反应性桥脑周围血管强化慢性淋巴细胞性炎症（CLIPPERS）：一例报告
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Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids with seizures and central pyrexia, in a patient requiring tracheal intubation and mechanical ventilation: A case report.一名需要气管插管和机械通气的患者出现慢性淋巴细胞性炎症伴脑桥血管周围强化，对类固醇治疗有反应，伴有癫痫发作和中枢性发热：病例报告
J Intensive Care Soc. 2018 May;19(2):167-170. doi: 10.1177/1751143717719644. Epub 2017 Jul 17.
2
A cerebral phenotype of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids: A case report and review of the literature.类固醇反应性伴有桥脑血管周围强化的慢性淋巴细胞炎症性脑病：病例报告及文献复习。
Mult Scler Relat Disord. 2018 Feb;20:159-163. doi: 10.1016/j.msard.2018.01.017. Epub 2018 Jan 31.
3
Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).类固醇反应性脑桥淋巴细胞血管周围浸润伴炎症的诊断标准（CLIPPERS）。
Brain. 2017 Sep 1;140(9):2415-2425. doi: 10.1093/brain/awx200.
4
Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI.CLIPPERS 综合征的广泛炎症可通过尸检和超高场 7T MRI 显示。
Neurol Neuroimmunol Neuroinflamm. 2016 Apr 20;3(3):e226. doi: 10.1212/NXI.0000000000000226. eCollection 2016 Jun.
5
Breathing and the nervous system.呼吸与神经系统。
Handb Clin Neurol. 2014;119:241-50. doi: 10.1016/B978-0-7020-4086-3.00017-5.
6
CLIPPERS: chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. Review of an increasingly recognized entity within the spectrum of inflammatory central nervous system disorders.CLIPPERS：伴有脑桥血管周围强化的慢性淋巴细胞性炎症，对类固醇治疗有反应。对炎症性中枢神经系统疾病范围内一种日益被认识的病症的综述。
Clin Exp Immunol. 2014 Mar;175(3):385-96. doi: 10.1111/cei.12204.
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Need for prolonged immunosupressive therapy in CLIPPERS--a case report.CLIPPERS 患者需要长期免疫抑制治疗——1 例报告。
BMC Neurol. 2013 May 24;13:49. doi: 10.1186/1471-2377-13-49.
8
Positional central apnea and vascular medullary compression.体位性中枢性睡眠呼吸暂停与血管性延髓压迫。
Neurology. 2012 Nov 20;79(21):2156-7. doi: 10.1212/WNL.0b013e3182752cc9. Epub 2012 Nov 7.
9
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).伴有桥脑血管周围强化的慢性淋巴细胞性炎症对类固醇反应良好（CLIPPERS）。
Brain. 2010 Sep;133(9):2626-34. doi: 10.1093/brain/awq164. Epub 2010 Jul 17.
10
Determination of the human brainstem respiratory control network and its cortical connections in vivo using functional and structural imaging.利用功能和结构成像在体内确定人类脑干呼吸控制网络及其皮质连接。
Neuroimage. 2009 Jan 15;44(2):295-305. doi: 10.1016/j.neuroimage.2008.09.007. Epub 2008 Sep 24.

偏侧味觉障碍、幻嗅与呼吸骤停：1例伴皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病（CLIPPERS）病例

Hemidysgeusia, phantosmia and respiratory arrest: a case of CLIPPERS.

作者信息

Nguyen Peter Baoviet, Prentice David, Brazel Robert, Leong Wai Kuen

机构信息

Department of Neurology, Royal Perth Hospital, Perth, Western Australia, Australia.

Perron Institute, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia.

出版信息

BMJ Case Rep. 2019 May 30;12(5):e230094. doi: 10.1136/bcr-2019-230094.

DOI:10.1136/bcr-2019-230094
PMID:31151979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6557413/
Abstract

A 56-year-old man presented with a relapse of likely chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) after a reduction of steroid dose. MRI demonstrated new perivascular FLuid-Attenuated Inversion Recovery (FLAIR) signal hyperintensity involving the dorsal pontomedullary junction and progressing inferiorly into the dorsal medulla oblongata. His admission to hospital was complicated by a respiratory arrest.

摘要

一名56岁男性在减少类固醇剂量后，出现了可能的类固醇反应性桥脑周围血管强化慢性淋巴细胞性炎症复发（CLIPPERS）。磁共振成像（MRI）显示新的血管周围液体衰减反转恢复序列（FLAIR）信号高增强，累及桥延髓背侧交界处，并向下延伸至延髓背侧。他入院时并发了呼吸骤停。