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抗前列腺素疗法在春季角结膜炎中的疗效。

Efficacy of antiprostaglandin therapy in vernal conjunctivitis.

作者信息

Meyer E, Kraus E, Zonis S

机构信息

Department of Ophthalmology, Rambam Medical Center, Haifa, Israel.

出版信息

Br J Ophthalmol. 1987 Jul;71(7):497-9. doi: 10.1136/bjo.71.7.497.

DOI:10.1136/bjo.71.7.497
PMID:3115287
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1041213/
Abstract

Twenty-seven patients with vernal conjunctivitis who remained symptomatic following treatment with corticosteroid drops and/or Opticrom drops (sodium cromoglycate 2%, benzalkonium chloride 0.01%) were treated with aspirin. Aspirin produced marked improvement in all patients apart from three. The possible mechanism of the efficacy of aspirin in vernal conjunctivitis is discussed.

摘要

27例春季结膜炎患者在用皮质类固醇滴眼液和/或色甘酸钠滴眼液(2%色甘酸钠、0.01%苯扎氯铵)治疗后仍有症状,接受了阿司匹林治疗。除3例患者外,阿司匹林使所有患者的症状都有显著改善。本文讨论了阿司匹林治疗春季结膜炎疗效的可能机制。

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1
Efficacy of antiprostaglandin therapy in vernal conjunctivitis.抗前列腺素疗法在春季角结膜炎中的疗效。
Br J Ophthalmol. 1987 Jul;71(7):497-9. doi: 10.1136/bjo.71.7.497.
2
Adjuvant therapy of aspirin and cromoglycate 2% eye drops in vernal conjunctivitis.阿司匹林和2%色甘酸钠滴眼液辅助治疗春季结膜炎。
Korean J Ophthalmol. 1989 Jun;3(1):42-6. doi: 10.3341/kjo.1989.3.1.42.
3
[Therapy of chronic allergic conjunctivitis with sodium cromoglycate (lecrolin)].
Vestn Oftalmol. 1997 Mar-Apr;113(2):21-2.
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Evaluation of topical cromolyn sodium in the treatment of vernal keratoconjunctivitis.局部用色甘酸钠治疗春季角结膜炎的评估。
Ophthalmology. 1988 Feb;95(2):194-201. doi: 10.1016/s0161-6420(88)33201-x.
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Treatment of vernal keratoconjunctivitis with topical cromolyn sodium.局部应用色甘酸钠治疗春季角结膜炎。
J Pediatr Ophthalmol Strabismus. 1978 Sep-Oct;15(5):326-9. doi: 10.3928/0191-3913-19780901-17.
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Nedocromil sodium eye drops are more effective than sodium cromoglycate eye drops for the long-term management of vernal keratoconjunctivitis.奈多罗米钠滴眼液在春季角结膜炎的长期治疗中比色甘酸钠滴眼液更有效。
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Evaluation of combined systemic aspirin and cromolyn sodium in intractable vernal catarrh.全身性阿司匹林与色甘酸钠联合治疗顽固性春季卡他性结膜炎的评估
Ann Ophthalmol. 1990 Aug;22(8):314-8.
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Topical sodium cromoglycate (Opticrom) relieves ongoing symptoms of allergic conjunctivitis within 2 minutes.局部用色甘酸钠(奥洛他定)可在2分钟内缓解过敏性结膜炎的持续症状。
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Role of disodium cromoglycate in vernal conjunctivitis.色甘酸钠在春季角结膜炎中的作用。
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Therapeutic options in ocular allergic disease.眼部过敏性疾病的治疗选择。
Drugs. 1995 Aug;50(2):208-21. doi: 10.2165/00003495-199550020-00002.
3
Levels of prostaglandin E2 and leukotriene B4 in tears of vernal conjunctivitis patients during a therapeutic trial with indomethacin.在使用消炎痛进行治疗试验期间,春季结膜炎患者泪液中前列腺素E2和白三烯B4的水平。
Doc Ophthalmol. 1994;85(3):247-57. doi: 10.1007/BF01664932.

本文引用的文献

1
A review of four hundred cases of vernal conjunctivitis.400例春季结膜炎的回顾。
Am J Ophthalmol. 1959 Feb;47(2):166-72. doi: 10.1016/s0002-9394(14)76417-7.
2
Mast cell ultrastructure. Comparison in contact lens-associated giant papillary conjunctivitis and vernal conjunctivitis.
Arch Ophthalmol. 1981 Jul;99(7):1266-72. doi: 10.1001/archopht.1981.03930020140019.
3
Clinical trial with 2% sodium cromoglycate (Opticrom) in vernal keratoconjunctivitis.2%色甘酸钠(Opticrom)治疗春季角结膜炎的临床试验。
Br J Ophthalmol. 1980 Jul;64(7):483-6. doi: 10.1136/bjo.64.7.483.
4
Differential inflammatory effects of arachidonic acid on rabbit conjunctiva and iris: a possible role of lipoxygenase in the conjunctival response.花生四烯酸对兔结膜和虹膜的不同炎症作用:脂氧合酶在结膜反应中的可能作用。
Adv Prostaglandin Thromboxane Res. 1980;8:1727-31.
5
Disodium cromoglycate (Intal) in the treatment of vernal kerato-conjunctivitis.色甘酸钠(咽泰)治疗春季角结膜炎
Trans Ophthalmol Soc U K (1962). 1971;91:491-9.
6
Inhibition of the ocular effects of sodium arachidonate by anti-inflammatory compounds.抗炎化合物对花生四烯酸钠眼部效应的抑制作用。
Prostaglandins. 1975 Feb;9(2):175-82. doi: 10.1016/0090-6980(75)90022-2.
7
Acetylation of prostaglandin synthase by aspirin.阿司匹林对前列腺素合酶的乙酰化作用。
Proc Natl Acad Sci U S A. 1975 Aug;72(8):3073-6. doi: 10.1073/pnas.72.8.3073.
8
Cromolyn effects on vernal keratoconjunctivitis in children.色甘酸钠对儿童春季角结膜炎的作用。
Arch Ophthalmol. 1977 Dec;95(12):2184-6. doi: 10.1001/archopht.1977.04450120090009.