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跛行和严重肢体缺血行血管介入治疗的患者在另一家医院的再入院与显著更高的死亡率相关。

Readmissions to an alternate hospital in patients undergoing vascular intervention for claudication and critical limb ischemia associated with significantly higher mortality.

机构信息

Department of Surgery, University of Miami Miller School of Medicine, Miami, Fla.

Department of Surgery, University of Miami Miller School of Medicine, Miami, Fla.

出版信息

J Vasc Surg. 2019 Dec;70(6):1960-1972. doi: 10.1016/j.jvs.2019.02.055. Epub 2019 May 29.

Abstract

BACKGROUND

Hospital readmissions with 30 days after vascular surgical interventions have been associated with increased morbidity, mortality, and cost. Readmission rates, now a Centers for Medicare and Medicaid Services quality measure, have been studied in databases that have excluded certain payer types and states and have not accounted for readmission to a hospital different from that of the index admission. More accurate and nationally representative data are needed, because this fragmentation of care could lead to flawed conclusions. The purpose of the present study was to examine the incidence and risk factors for readmission to a nonindex hospital for patients admitted for claudication or critical limb ischemia (CLI). We also examined how this disruption of patient care affects mortality.

METHODS

The 2013 to 2014 Nationwide Readmissions Database was queried for all patients admitted for claudication or CLI who had undergone angioplasty, lower extremity bypass, or aortobifemoral bypass. The outcomes of interest were 30- and 365-day readmission rates to any hospital, 30- and 365-day readmission rates to a nonindex hospital, and mortality rates. Multivariable logistic regression was used to identify risk factors for readmission to a nonindex hospital. The most common readmission diagnoses and diagnosis-related groups were identified.

RESULTS

A total of 92,769 patients had been admitted with peripheral vascular disease (33,055 with claudication and 59,714 with CLI). The 30- and 365-day readmission rate was 8.97% and 21.49% and 19.26% and 40.36%, for claudication and CLI, respectively. Of the 30- and 365-day readmissions, 20.47% and 24.92% had occurred at a nonindex hospital, respectively. Significantly higher mortality rates were found for patients with 30- or 365-day readmissions to different hospitals (odds ratio, 1.4 and 1.8, respectively). Multivariable analysis revealed that procedural indication and angioplasty are not significant risk factors for readmission to a different hospital. However, female sex, length of stay >7 days, and Charlson Comorbidity Index >3 remained significant risk factors for nonindex readmissions. The most common disease groups for nonindex readmission were "septicemia and disseminated infections" (6.5%), "heart failure" (6.4%), "other vascular procedures" (6.1%), and "amputation of lower limb except toes" (4.0%).

CONCLUSIONS

Previously unreported, ≥1 in 4 readmissions after lower extremity vascular procedures for peripheral vascular disease will occur at a nonindex hospital. This fragmentation of care is associated with increased mortality and has serious implications for guiding outcome and quality measures. With a sizeable portion of patients missed by current metrics, concern exists that providers are using flawed data. Further study into social- and patient-specific risk factors might provide methods to prevent these readmissions and improve outcomes in this difficult patient population.

摘要

背景

血管外科手术后 30 天内的医院再入院与发病率、死亡率和成本增加有关。现在,再入院率是医疗保险和医疗补助服务中心的一项质量衡量标准,已在排除某些支付类型和州的数据库中进行了研究,但没有考虑到与索引入院不同的医院的再入院。需要更准确和具有全国代表性的数据,因为这种护理的碎片化可能会导致有缺陷的结论。本研究的目的是检查因跛行或严重肢体缺血(CLI)入院的患者到非索引医院再入院的发生率和危险因素。我们还研究了这种患者护理的中断如何影响死亡率。

方法

2013 年至 2014 年全国再入院数据库中检索了所有接受血管成形术、下肢旁路或腹主动脉-股动脉旁路手术的因跛行或 CLI 入院的患者。感兴趣的结果是任何医院的 30 天和 365 天再入院率、非索引医院的 30 天和 365 天再入院率以及死亡率。多变量逻辑回归用于确定非索引医院再入院的危险因素。确定了最常见的再入院诊断和诊断相关组。

结果

共有 92769 名患者因外周血管疾病入院(33055 名因跛行和 59714 名因 CLI)。30 天和 365 天的再入院率分别为 8.97%和 21.49%和 19.26%和 40.36%,分别为跛行和 CLI。30 天和 365 天的再入院中有 20.47%和 24.92%分别发生在非索引医院。不同医院 30 天或 365 天再入院的患者死亡率明显较高(比值比分别为 1.4 和 1.8)。多变量分析显示,手术适应证和血管成形术不是非索引医院再入院的显著危险因素。然而,女性、住院时间>7 天和 Charlson 合并症指数>3 仍然是非索引再入院的显著危险因素。非索引再入院最常见的疾病组是“败血症和播散性感染”(6.5%)、“心力衰竭”(6.4%)、“其他血管手术”(6.1%)和“下肢除脚趾外截肢”(4.0%)。

结论

先前未报告的外周血管疾病下肢血管手术后,≥1/4 的再入院将发生在非索引医院。这种护理的碎片化与死亡率增加有关,并对指导结果和质量措施有严重影响。由于目前的指标遗漏了相当一部分患者,人们担心提供者正在使用有缺陷的数据。进一步研究社会和患者特定的危险因素可能提供预防这些再入院和改善这一困难患者群体预后的方法。

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