The Cognitive Neurophysiology Laboratory, Department of Pediatrics & Neuroscience, Albert Einstein College of Medicine & Montefiore Medical Center, Bronx, NY, USA.
Department of Medicine, Columbia University College of Physicians and Surgeons, Columbia University Medical Center, New York Presbyterian Hospital, New York, NY, USA.
Cogn Neurosci. 2020 Jan;11(1-2):71-91. doi: 10.1080/17588928.2019.1627303. Epub 2019 Jul 1.
Neural entrainment and alpha oscillatory power (8-14 Hz) are mechanisms of selective attention. The extent to which these two mechanisms interact, especially in the context of visuospatial attention, is unclear. Here, we show that spatial attention to a delta-frequency, rhythmic visual stimulus in one hemifield results in phase-amplitude coupling between the delta-phase of an entrained frontal source and alpha power generated by ipsilateral visuocortical regions. The driving of ipsilateral alpha power by frontal delta also correlates with task performance. Our analyses suggest that neural entrainment may serve a previously underappreciated role in coordinating macroscale brain networks and that inhibition of processing by alpha power can be coupled to an attended temporal structure. Finally, we note that the observed coupling bolsters one dominant hypothesis of modern cognitive neuroscience, that macroscale brain networks and distributed neural computation are coordinated by oscillatory synchrony and cross-frequency interactions.
神经同步和 alpha 振荡功率（8-14 Hz）是选择性注意的机制。这两种机制相互作用的程度尚不清楚，尤其是在视空间注意的情况下。在这里，我们表明，对一个视野中的 delta 频率、节奏性视觉刺激的空间注意导致了同步的额源的 delta 相位和由同侧视皮质区域产生的 alpha 功率之间的相位-振幅耦合。额部 delta 驱动同侧 alpha 功率与任务表现相关。我们的分析表明，神经同步可能在协调宏观脑网络方面发挥了以前未被充分认识的作用，并且 alpha 功率对处理的抑制作用可以与注意的时间结构耦合。最后，我们注意到，观察到的耦合支持了现代认知神经科学的一个主要假设，即宏观脑网络和分布式神经计算是由振荡同步和跨频相互作用协调的。
