Rexroad Caird, Vallet Jeffrey, Matukumalli Lakshmi Kumar, Reecy James, Bickhart Derek, Blackburn Harvey, Boggess Mark, Cheng Hans, Clutter Archie, Cockett Noelle, Ernst Catherine, Fulton Janet E, Liu John, Lunney Joan, Neibergs Holly, Purcell Catherine, Smith Timothy P L, Sonstegard Tad, Taylor Jerry, Telugu Bhanu, Eenennaam Alison Van, Tassell Curtis P Van, Wells Kevin
Office of National Programs, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD, United States.
National Institute of Food and Agriculture, United States Department of Agriculture, Washington, DC, United States.
Front Genet. 2019 May 16;10:327. doi: 10.3389/fgene.2019.00327. eCollection 2019.
In 2008, a consortium led by the Agricultural Research Service (ARS) and the National Institute for Food and Agriculture (NIFA) published the "Blueprint for USDA Efforts in Agricultural Animal Genomics 2008-2017," which served as a guiding document for research and funding in animal genomics. In the decade that followed, many of the goals set forth in the blueprint were accomplished. However, several other goals require further research. In addition, new topics not covered in the original blueprint, which are the result of emerging technologies, require exploration. To develop a new, updated blueprint, ARS and NIFA, along with scientists in the animal genomics field, convened a workshop titled "Genome to Phenome: A USDA Blueprint for Improving Animal Production" in November 2017, and these discussions were used to develop new goals for the next decade. Like the previous blueprint, these goals are grouped into the broad categories "Science to Practice," "Discovery Science," and "Infrastructure." New goals for characterizing the microbiome, enhancing the use of gene editing and other biotechnologies, and preserving genetic diversity are included in the new blueprint, along with updated goals within many genome research topics described in the previous blueprint. The updated blueprint that follows describes the vision, current state of the art, the research needed to advance the field, expected deliverables, and partnerships needed for each animal genomics research topic. Accomplishment of the goals described in the blueprint will significantly increase the ability to meet the demands for animal products by an increasing world population within the next decade.
2008年,由美国农业研究局(ARS)和美国国家粮食与农业研究所(NIFA)牵头的一个财团发布了《2008 - 2017年美国农业部农业动物基因组学研究蓝图》,该蓝图作为动物基因组学研究和资金投入的指导文件。在随后的十年里,蓝图中设定的许多目标都得以实现。然而,其他一些目标仍需进一步研究。此外,由于新兴技术产生的一些原蓝图未涵盖的新主题也需要探索。为了制定一份新的、更新后的蓝图,ARS、NIFA以及动物基因组学领域的科学家们于2017年11月召开了一次题为“从基因组到表型组:美国农业部改善动物生产的蓝图”的研讨会,并利用这些讨论为未来十年制定新目标。与之前的蓝图一样,这些目标分为“科学转化为实践”“探索性科学”和“基础设施”三大类。新蓝图纳入了表征微生物组、加强基因编辑和其他生物技术应用以及保护遗传多样性的新目标,同时也更新了前蓝图中许多基因组研究主题下的目标。接下来的这份更新后的蓝图描述了每个动物基因组学研究主题的愿景、当前技术水平、推动该领域发展所需的研究、预期成果以及所需的合作关系。实现蓝图中描述的目标将显著提高在未来十年内满足不断增长的世界人口对动物产品需求的能力。