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STOPP/START标准在长期护理医院老年多病患者中的适用性。

Applicability of the STOPP/START criteria to older polypathological patients in a long-term care hospital.

作者信息

Hernandez Martin Julia, Merino-Sanjuán Virginia, Peris-Martí Juan, Correa-Ballester Marta, Vial-Escolano Raquel, Merino-Sanjuán Matilde

机构信息

Farmacia, Hospital San José, Teruel, Spain.

Instituto Interuniversitario Reconocimiento Molecular y Desarrollo Tecnológico, Departamento de Farmacia y Tecnología Farmacéutica y Parasitología de la Universidad de Valencia., Valencia, Spain.

出版信息

Eur J Hosp Pharm. 2018 Nov;25(6):310-316. doi: 10.1136/ejhpharm-2017-001262. Epub 2017 Aug 9.

Abstract

OBJECTIVES

To analyse the applicability of the STOPP/START criteria as a tool to identify patients with potentially inappropriate medications (PIM) during pharmaceutical validation of prescriptions in a long-term care hospital, to identify risk factors for PIM and to characterise the physiological systems and drugs more frequently associated with these PIM.

METHODS

An interventional, prospective and longitudinal study was conducted in polypathological patients aged >65 years. Usual pharmaceutical care and the STOPP/START criteria were used to identify PIM and to plan pharmaceutical interventions at admission. At discharge, the discharge summaries were reviewed using the STOPP/START criteria.

RESULTS

112 patients were included. The prevalence of patients with PIM at admission was 76.8%. The STOPP criteria identified a high number of PIM and almost all entailed pharmaceutical intervention. On the other hand, most of the START criteria identified did not entail pharmaceutical intervention. Usual pharmaceutical care detected a different type of PIM; a high percentage of pharmaceutical interventions to resolve them were accepted. At discharge, the prevalence of patients with PIM was 61.3%. At admission, none of the analysed variables was associated with the PIM identified using any of the tools. At discharge STOPP criteria identified a higher percentage of patients with PIM in the geriatric outpatient consultation group.

CONCLUSIONS

The prevalence of PIM in older polypathological patients is high. The STOPP criteria are useful for reducing inappropriate prescribing during the pharmaceutical validation process. In contrast, routine incorporation of the START criteria in the pharmaceutical validation may be not necessary in a hospital of this type.

摘要

目的

分析STOPP/START标准作为一种工具在长期护理医院处方药物验证过程中识别潜在不适当用药(PIM)患者的适用性,识别PIM的危险因素,并描述与这些PIM更常相关的生理系统和药物。

方法

对65岁以上的多病患者进行了一项干预性、前瞻性和纵向研究。采用常规药物治疗和STOPP/START标准识别PIM,并在入院时规划药物干预措施。出院时,使用STOPP/START标准对出院小结进行审查。

结果

纳入112例患者。入院时PIM患者的患病率为76.8%。STOPP标准识别出大量PIM,几乎所有PIM都需要药物干预。另一方面,大多数识别出的START标准不需要药物干预。常规药物治疗检测到不同类型的PIM;为解决这些问题而进行的药物干预中有很高比例被接受。出院时,PIM患者的患病率为61.3%。入院时,所分析的变量均与使用任何一种工具识别出的PIM无关。出院时,STOPP标准在老年门诊咨询组中识别出更高比例的PIM患者。

结论

老年多病患者中PIM的患病率很高。STOPP标准有助于在药物验证过程中减少不适当的处方。相比之下,在这类医院中,将START标准常规纳入药物验证可能没有必要。

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