Burke Andrea, O'Driscoll Michelle, Crowley Erin K, Dhubhlaing Ciara Ni
Pharmacy Department, St. Patrick's Mental Health Services, Dublin, Ireland.
Pharmaceutical Care Research Group, School of Pharmacy, University College Cork, Cork, Ireland.
Explor Res Clin Soc Pharm. 2023 Mar 23;9:100245. doi: 10.1016/j.rcsop.2023.100245. eCollection 2023 Mar.
There is a scarcity of research in applying the Screening Tool of Older Person's Prescriptions/Screening Tool to Alert to Right Treatment (STOPP/START) criteria to older adults admitted to a psychiatric hospital.
The primary aim of this study was to determine the extent of polypharmacy in older adults admitted to a psychiatric hospital and to assess the number of STOPP/START triggers detected and recommended by pharmacists. Secondary objectives include evaluating if the STOPP/START criteria is a useful tool to improve prescribing in this setting by assessing the implementation rates of STOPP/START triggers.
This was a prospective, longitudinal study in a psychiatry inpatient setting. Data were collected over a 7-week period. Explicit informed consent was obtained from participants. Medication reconciliation was completed and participants' medications were reviewed using STOPP/START criteria. The number of STOPP/START triggers detected, recommended and implemented was recorded.
Sixty-two patients were included in the study. Ninety-four percent were prescribed ≥5 medications and 55% were prescribed ≥10 medications on admission. The mean number of medications prescribed per patient increased from 10 on admission to 12 at follow-up. Of 174 Potential Inappropriate Medications (PIMs) detected, 41% were recommended for review and, of these only 31% were implemented. 27% of the 77 Potential Prescribing Omissions (PPOs) detected were recommended for review and only 23% of those were implemented.
STOPP/START did not reduce the prevalence of polypharmacy in this setting. The implementation rates observed in this study were much lower than those observed in non-psychiatric settings.
将老年人处方筛查工具/治疗正确警报筛查工具(STOPP/START)标准应用于入住精神病医院的老年人的研究较少。
本研究的主要目的是确定入住精神病医院的老年人的多重用药程度,并评估药剂师检测到并推荐的STOPP/START触发因素的数量。次要目标包括通过评估STOPP/START触发因素的实施率,评估STOPP/START标准是否是改善该环境中处方的有用工具。
这是一项在精神病住院环境中的前瞻性纵向研究。在7周内收集数据。获得了参与者的明确知情同意。完成了用药核对,并使用STOPP/START标准对参与者的药物进行了审查。记录检测到、推荐并实施的STOPP/START触发因素的数量。
62名患者纳入研究。94%的患者入院时开具了≥5种药物,55%的患者开具了≥10种药物。每位患者的平均用药数量从入院时的10种增加到随访时的12种。在检测到的174种潜在不适当药物(PIM)中,41%被建议进行审查,其中只有31%得到实施。在检测到的77种潜在处方遗漏(PPO)中,27%被建议进行审查,其中只有23%得到实施。
在这种情况下,STOPP/START并未降低多重用药的患病率。本研究中观察到的实施率远低于非精神病环境中的实施率。