Department of Otolaryngology-Head and Neck Surgery.
Department of Urology.
Otol Neurotol. 2019 Sep;40(8):1026-1033. doi: 10.1097/MAO.0000000000002302.
To determine the audiologic improvement after middle cranial fossa (MCF) approach to repair spontaneous cerebrospinal fluid (sCSF) leaks.
Retrospective cohort study.
Tertiary referral center.
Twenty-four consecutive patients (27 ears) with temporal bone sCSF leak over a 4-year period. Patient age, sex, ethnicity, body mass index (BMI), location of CSF leak, recurrence of CSF leak, and presence of encephalocele(s) were recorded.
Audiometric testing in patients undergoing MCF repair of temporal bone sCSF leak.
Comparison of preoperative and postoperative pure-tone average (PTA), air-bone gap (ABG), and word recognition score (WRS) in the sCSF leak ear.
Out of 27 ears, 55% had multiple tegmen defects and 82% had more than or equal to 1 encephaloceles. There were no recurrent CSF leaks at a median follow up of 4 months. The mean (SD) preoperative PTA and ABG were 40.58 [15.67] and 16.44 [6.93] dB, respectively. There was significant improvement in mean PTA (10.28 [8.01] dB; p < 0.001; Cohen d = 0.95) and ABG (9.31 [7.16] dB; p < 0.001; Cohen d = 0.88) after sCSF repair. Mean WRS improved (by 3.07 [6.11] %; p = 0.024; Cohen d = 0.46) from a mean preoperative WRS of 93.16 [9.34]% to a mean postoperative WRS of 96.26 [6.49]%.
MCF approach for repair of sCSF leaks yields significant improvement in conductive hearing loss and is highly effective in management of the entire lateral skull base where multiple bony defects are often identified.
确定经中颅窝(MCF)入路修复自发性脑脊液(sCSF)漏的听力改善情况。
回顾性队列研究。
三级转诊中心。
4 年内连续 24 例(27 耳)颞骨 sCSF 漏患者。记录患者年龄、性别、种族、体重指数(BMI)、CSF 漏位置、CSF 漏复发和有无脑膨出。
对行 MCF 修复颞骨 sCSF 漏的患者进行听力测试。
sCSF 漏耳术前和术后纯音平均听阈(PTA)、气骨导差(ABG)和言语识别率(WRS)的比较。
27 耳中,55%有多个鼓室天盖缺损,82%有 1 个或多个脑膨出。中位随访 4 个月时无复发性 CSF 漏。术前平均 PTA(40.58[15.67]dB)和 ABG(16.44[6.93]dB)。sCSF 修复后,平均 PTA(10.28[8.01]dB;p<0.001;Cohen d=0.95)和 ABG(9.31[7.16]dB;p<0.001;Cohen d=0.88)均有显著改善。WRS 从术前的 93.16[9.34]%平均提高(提高 3.07[6.11]%;p=0.024;Cohen d=0.46)至术后的 96.26[6.49]%。
MCF 入路修复 sCSF 漏可显著改善传导性听力损失,对多个骨缺损常被识别的整个外侧颅底的治疗非常有效。