Department of Otolaryngology - Head and Neck Surgery, West Virginia University, USA.
Department of Neurosurgery, West Virginia University, USA.
Am J Otolaryngol. 2024 Jul-Aug;45(4):104345. doi: 10.1016/j.amjoto.2024.104345. Epub 2024 Apr 27.
To assess the audiometric outcomes following surgical repair of spontaneous temporal bone cerebrospinal fluid otorrhea and compare different surgical approaches.
Retrospective review of adults (≥18 years old) who underwent repair of spontaneous CSF leak between 2011 and 2022. Audiometric outcomes were compared across the three surgical groups: transmastoid, middle cranial fossa and combined.
Thirty-nine patients (40 ears) met the inclusion criteria (71.8 % females; mean age 59.77 +/- 12.4). Forty-two percent underwent transmastoid, 12.5 % middle cranial fossa and 45 % transmastoid-middle cranial fossa. Four patients (10 %) had recurrence, 3 in the transmastoid group and 1 in the combined approach. The mean change in air-bone gap (ABG) for all patients (postoperative-preoperative) was -7.4 (paired t-test, p-value = 0.0003). The postoperative ABG was closed in 28 (70 %) ears (postoperative ABG ≤ 15). The mean change in pure tone average (PTA) for all patients (postoperative-preoperative) was -4.1 (paired t-test, p-value = 0.13). The mean change in word recognition scores (WRS) for all patients (postoperative-preoperative) was -3 (paired t-test, p-value = 0.35). On multivariable analysis (controlling for site and reconstruction material), there was no significant difference in ABG, PTA and WRS change between surgical groups.
Transmastoid, middle cranial fossa and combined approaches are all effective in treatment of spontaneous CSF leaks and all showed mean decrease in post-operative ABG. Transmastoid approach showed the greatest decrease in ABG and PTA (although middle cranial fossa approach shows the greatest decrease, when excluding profound hearing loss in a patient with superior canal dehiscence). Further studies comparing audiometric outcomes are needed.
评估手术修复自发性颞骨脑脊液耳漏的听力结果,并比较不同的手术方法。
回顾性分析 2011 年至 2022 年间接受自发性 CSF 漏修复的成年人(≥18 岁)。比较三种手术组(经乳突、中颅窝和联合)的听力结果。
39 例(40 耳)符合纳入标准(71.8%为女性;平均年龄 59.77±12.4 岁)。42%接受经乳突入路,12.5%接受中颅窝入路,45%接受经乳突-中颅窝联合入路。4 例(10%)患者复发,经乳突组 3 例,联合入路组 1 例。所有患者(术后-术前)气骨导差(ABG)的平均变化为-7.4(配对 t 检验,p 值=0.0003)。28 耳(70%)ABG 闭合(术后 ABG≤15)。所有患者(术后-术前)纯音听阈平均值(PTA)的平均变化为-4.1(配对 t 检验,p 值=0.13)。所有患者(术后-术前)言语识别率(WRS)的平均变化为-3(配对 t 检验,p 值=0.35)。多变量分析(控制部位和重建材料)显示,三组手术在 ABG、PTA 和 WRS 变化方面无显著差异。
经乳突、中颅窝和联合入路均能有效治疗自发性 CSF 漏,且术后 ABG 均有平均下降。经乳突入路的 ABG 和 PTA 下降最大(尽管中颅窝入路在排除上半规管裂患者的严重听力损失时显示 ABG 和 PTA 下降最大)。需要进一步研究比较听力结果。