Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University, Nashville, Tennessee, USA.
Otolaryngol Head Neck Surg. 2020 Jun;162(6):942-949. doi: 10.1177/0194599820911720. Epub 2020 Mar 24.
To investigate audiometric outcomes and incidence of chronic ear disease following lateral skull base repair (LSBR) of cerebrospinal fluid (CSF) leaks.
Retrospective review.
Tertiary skull base center.
Consecutive adults undergoing LSBR of CSF leaks between 2012 and 2018 were reviewed. Audiometric data included mean air conduction pure-tone average (PTA), air-bone gap (ABG), speech recognition threshold (SRT), and word recognition score (WRS). The incidence and management of the following were collected: effusion, retraction, otitis media and externa, perforation, and cholesteatoma.
Seventy-three patients underwent transmastoid (n = 5), middle cranial fossa (n = 2), or combined approach (n = 67) for repair of spontaneous leaks (sCSFLs, n = 41) and those occurring in the setting of chronic ear disease (ceCSFLs, n = 32). ABG decreased 7.23 dB ( = .01) in sCSFL patients. Perforations ( = .01) were more likely in ceCSFL. No sCSFL patient developed a cholesteatoma, perforation, or infection. Effusions (n = 7) were transient, and retractions (n = 2) were managed conservatively in the sCSFL cohort. Eight ceCSFL patients required tubes, 3 underwent tympanoplasties with (n = 2) and without (n = 1) ossicular chain reconstruction (OCR), and 1 had tympanomastoidectomy with OCR.
Lateral skull base repair of CSF leaks maintained or improved hearing. Patients with preexisting chronic ear disease were more likely to require additional intervention to sustain adequate middle ear aeration compared to the sCSFL cohort. LSBR of sCSFL does not appear to increase risk for developing chronic ear disease.
研究颅底外侧修复(LSBR)脑脊液(CSF)漏后听力结果和慢性耳部疾病的发生率。
回顾性研究。
三级颅底中心。
回顾了 2012 年至 2018 年间连续进行 LSBR 治疗 CSF 漏的成年人。听力数据包括平均气导纯音平均(PTA)、气骨间隙(ABG)、言语识别阈(SRT)和言语识别率(WRS)。收集了以下内容的发生率和处理方法:积液、回缩、中耳和外耳炎、穿孔和胆脂瘤。
73 例患者接受经乳突(n = 5)、中颅窝(n = 2)或联合入路(n = 67)修复自发性漏(sCSFL,n = 41)和慢性耳部疾病(ceCSFL,n = 32)。sCSFL 患者的 ABG 下降了 7.23dB(P =.01)。ceCSFL 患者穿孔的可能性更大(P =.01)。无 sCSFL 患者发生胆脂瘤、穿孔或感染。积液(n = 7)为一过性,sCSFL 患者中回缩(n = 2)经保守治疗。8 例 ceCSFL 患者需要置管,3 例行鼓室成形术,其中 2 例(n = 2)和 1 例(n = 1)行听骨链重建(OCR),1 例行乳突-鼓室成形术伴 OCR。
颅底外侧修复 CSF 漏可维持或改善听力。与 sCSFL 组相比,患有慢性耳部疾病的患者需要额外的干预措施来维持中耳适当的通气。LSBR 治疗 sCSFL 似乎不会增加发生慢性耳部疾病的风险。