Ng Jia Hui, Bala Arul, Hendriks Thomas, Kuthubutheen Jafri
Department of Otolaryngology and Head and Neck Surgery, Sir Charles Gairdner Hospital, Nedlands, Western Australia.
Department of Otolaryngology and Head and Neck Surgery, Singapore General Hospital, Singapore, Singapore.
J Laryngol Otol. 2024 Oct 21;139(5):1-4. doi: 10.1017/S0022215124001294.
The aim of this study is to investigate hearing outcomes in patients who have undergone cerebrospinal fluid (CSF) leak repair via a middle cranial fossa (MCF) approach and to identify any variables that influence post-operative hearing outcomes.
This is a multi-centre study. A total of 65 patients who underwent an MCF approach CSF leak repair were included. Retrospective case review was conducted to collect patient demographic and clinical data including pre- and post-operative audiometry.
A total of 65 patients were included: 9 patients (9.2per cent) had an encephalocele confirmed on magnetic resonance (MR) imaging, whilst the remaining patients had biochemically confirmed, beta-trace protein positive CSF leaks. Post-operatively, there was a statistically significant improvement in both bone conduction (Z = -3.71, < 0.001) and air conduction thresholds (Z = -5.82, < 0.001). None of the studied variables were found to be associated with the degree of hearing improvement.
The MCF approach for CSF leak repair yields favorable audiological outcomes.
本研究旨在调查经中颅窝(MCF)入路进行脑脊液(CSF)漏修补术患者的听力结果,并确定影响术后听力结果的任何变量。
这是一项多中心研究。共纳入65例行MCF入路CSF漏修补术的患者。通过回顾性病例审查收集患者的人口统计学和临床数据,包括术前和术后听力测定。
共纳入65例患者:9例(9.2%)经磁共振(MR)成像证实有脑膨出,其余患者经生化证实为β-微球蛋白阳性CSF漏。术后,骨传导(Z = -3.71,P < 0.001)和气传导阈值(Z = -5.82,P < 0.001)均有统计学显著改善。未发现所研究的变量与听力改善程度相关。
MCF入路进行CSF漏修补术可产生良好的听力学结果。