Science Writer, New York, New York.
Bill & Melinda Gates Foundation, Seattle, Washington.
Ann N Y Acad Sci. 2020 Feb;1462(1):14-26. doi: 10.1111/nyas.14235. Epub 2019 Oct 28.
Vaccines have been incredibly successful at stemming the morbidity and mortality of infectious diseases worldwide. However, there are still no effective vaccines for many serious and potentially preventable infectious diseases. Advances in vaccine technology, including new delivery methods and adjuvants, as well as progress in systems biology and an increased understanding of the human immune system, hold the potential to address these issues. In addition, maternal immunization has opened an avenue to address infectious diseases in neonates and very young infants. This report summarizes the presentations from a 1-day symposium at the New York Academy of Sciences entitled "Innovative Vaccines against Resistant Infectious Diseases and Emerging Threats," held on May 20, 2019.
疫苗在遏制全球传染病的发病率和死亡率方面取得了令人难以置信的成功。然而，对于许多严重且可能可预防的传染病，目前仍没有有效的疫苗。疫苗技术的进步，包括新的传递方法和佐剂，以及系统生物学的进步和对人类免疫系统的深入了解，有可能解决这些问题。此外，母体免疫为解决新生儿和非常年幼婴儿的传染病开辟了一条途径。本报告总结了 2019 年 5 月 20 日在纽约科学院举行的题为“抗耐药性传染病和新兴威胁的创新疫苗”的为期 1 天的研讨会的报告。
