希腊老年人主观认知下降、轻度认知障碍和痴呆患者蒙特利尔认知评估的常模数据。

Normative Data for the Montreal Cognitive Assessment in Greek Older Adults With Subjective Cognitive Decline, Mild Cognitive Impairment and Dementia.

机构信息

1 Greek Association of Alzheimer's Disease and Related Disorders, Thessaloniki, Greece.

2 Laboratory of Psychology, Section of Cognitive and Experimental Psychology, School of Psychology, Aristotle University of Thessaloniki (AUTh), Thessaloniki, Greece.

出版信息

J Geriatr Psychiatry Neurol. 2019 Sep;32(5):265-274. doi: 10.1177/0891988719853046. Epub 2019 Jun 3.

DOI:10.1177/0891988719853046

PMID:31159629

Abstract

OBJECTIVE

The aim of the study was to provide normative data for the MoCA in a Greek cohort of people older than 60 years who meet criteria for subjective cognitive decline (SCD), mild cognitive impairment (MCI), or dementia in order to optimize cutoff scores for each diagnostic group.

METHOD

Seven hundred forty-six community-dwelling older adults, visitors of the Day Center of Alzheimer Hellas were randomly chosen. Three hundred seventy-nine of them met the criteria for dementia, 245 for MCI and 122 for SCD.

RESULTS

Initial statistical analyses showed that the total MoCA score is not affected by gender ( = .164), or age ( = .144) but is affected by educational level ( < .001). A cutoff score of 23 for low educational level (≤6 years) can distinguish people with SCD from MCI (sensitivity 71.4%, specificity 84.2%), while 26 is the cutoff score for middle educational level (7-12 years; sensitivity 73.2%, specificity 67.0%) and high educational level (≥13 years; sensitivity 77.6%, specificity 74.7%). Montreal Cognitive Assessment can discriminate older adults with SCD from dementia, with a cutoff score of 20 for low educational level (sensitivity 100%, specificity 92.3%) and a cutoff score 23 for middle educational level (sensitivity 97.6%, specificity 92.7%) and high educational level (sensitivity 98.5%, specificity 100%).

CONCLUSION

Montreal Cognitive Assessment is not affected by age or gender but is affected by the educational level. The discriminant potential of MoCA between SCD and MCI is good, while the discrimination of SCD from dementia is excellent.

摘要

目的

本研究旨在为希腊 60 岁以上人群提供 MoCA 的常模数据，这些人群符合主观认知下降（SCD）、轻度认知障碍（MCI）或痴呆的标准，以便为每个诊断组优化截断分数。

方法

我们随机选择了 746 名居住在社区的老年人，他们是阿尔茨海默病希腊日中心的访客。其中 379 人符合痴呆标准，245 人符合 MCI 标准，122 人符合 SCD 标准。

结果

初步统计分析表明，MoCA 的总分不受性别（ =.164）或年龄（ =.144）的影响，但受教育程度（ <.001）的影响。对于低教育水平（≤6 年），23 分的截断分数可以将 SCD 患者与 MCI 患者区分开来（敏感性 71.4%，特异性 84.2%），而 26 分是中等教育水平（7-12 年；敏感性 73.2%，特异性 67.0%）和高教育水平（≥13 年；敏感性 77.6%，特异性 74.7%）的截断分数。蒙特利尔认知评估可以区分 SCD 和痴呆患者，低教育水平的截断分数为 20 分（敏感性 100%，特异性 92.3%），中等教育水平的截断分数为 23 分（敏感性 97.6%，特异性 92.7%）和高教育水平（敏感性 98.5%，特异性 100%）。