School of Pharmacy, Guangdong Pharmaceutical Univ., Guangzhou, 510006, China.
School of Food Science and Engineering, South China Univ. of Technology, Guangzhou, 560640, China.
J Food Sci. 2019 Jun;84(6):1592-1599. doi: 10.1111/1750-3841.14623. Epub 2019 Jun 4.
The purpose of this study was to produce and characterize an inclusion complex between β-cyclodextrin (β-CD) and Exocarpium Citri Grandis essential oil (EEO), and to evaluate its antioxidant properties. The volatile compounds of EEO were characterized by gas chromatography-mass spectrometer. A comparison of the β-CD, EEO, and the physical mixture with the inclusion complex revealed differences in their thermal stabilities and morphologies, which confirmed the formation of the β-CD-EEO inclusion complex. Complexed with β-CD, the β-CD-EEO inclusion complex showed a higher stability and antioxidant activity when compared with physical mixture and EEO. Therefore, β-CD can be used to form inclusion complexes with EEO to expand its potential applications in the food and drug industries. PRACTICAL APPLICATION: Exocarpium Citri Grandis is rich in essential oil and other ingredients. The optimized extraction, constituent composition, and encapsulation of EEO in β-CD were investigated in this study. The results showed that the encapsulation process increased the antioxidant activity and stability of EEO, which provides both fundamental and practical knowledge for the application of EEO in the food and drug industries.
本研究旨在制备和表征β-环糊精（β-CD）与陈皮挥发油（EEO）的包合物，并评价其抗氧化性能。采用气相色谱-质谱联用技术对 EEO 的挥发性成分进行了表征。比较了β-CD、EEO 以及与包合物的物理混合物的热稳定性和形态差异，证实了β-CD-EEO 包合物的形成。与β-CD 复合后，β-CD-EEO 包合物的稳定性和抗氧化活性均高于物理混合物和 EEO。因此，β-CD 可用于与 EEO 形成包合物，以扩大其在食品和药品工业中的潜在应用。实际应用：陈皮富含挥发油和其他成分。本研究考察了 EEO 在β-CD 中的优化提取、成分组成和包封。结果表明，包封过程提高了 EEO 的抗氧化活性和稳定性，为 EEO 在食品和药品工业中的应用提供了基础和实际知识。
