Kim Jinhee, Bae Jong-Myon
Jeju Center for Infectious Diseases Control and Prevention, Jeju, Korea.
Department of Preventive Medicine, Jeju National University School of Medicine, Jeju, Korea.
J Prev Med Public Health. 2019 May;52(3):195-199. doi: 10.3961/jpmph.18.289. Epub 2019 Apr 3.
Jeju Province is well known as the region showing the highest incidence of severe fever with thrombocytopenia syndrome (SFTS) in South Korea. The aim of this study was to evaluate the epidemiological and clinical characteristics of SFTS patients in Jeju Province.
The primary data for this study were obtained from the Integrated Diseases and Health Control System of the Korea Centers for Disease Control and Prevention (KCDCIS). The selection criteria were confirmed cases of SFTS with a residence listed in Jeju Province at the time of diagnosis, reported to the KCDCIS between July 16, 2014 and November 30, 2018.
Of 55 confirmed cases of SFTS, the case fatality rate was 10.9% (95% confidence interval [CI], 4.1 to 22.2). The most common presenting symptoms at diagnosis of severe fever, myalgia, and diarrhea had incidences of 83.6% (95% Cl, 71.2 to 92.2), 45.5% (95% Cl, 32.0 to 59.5), and 40.0% (95% CI, 27.0 to 54.1), respectively.
Compared to SFTS patients nationwide in 2013-2015, the subjects of this study exhibited a lower case fatality rate and had a lower incidence of severe fever, myalgia, and confusion.
济州岛是韩国严重发热伴血小板减少综合征(SFTS)发病率最高的地区。本研究旨在评估济州岛SFTS患者的流行病学和临床特征。
本研究的原始数据来自韩国疾病控制与预防中心的综合疾病与健康控制系统(KCDCIS)。选择标准为2014年7月16日至2018年11月30日期间报告给KCDCIS的确诊SFTS病例,诊断时居住在济州岛。
在55例确诊的SFTS病例中,病死率为10.9%(95%置信区间[CI],4.1至22.2)。诊断时最常见的症状为高热、肌痛和腹泻,发生率分别为83.6%(95%CI,71.2至92.2)、45.5%(95%CI,32.0至59.5)和40.0%(95%CI,27.0至54.1)。
与2013 - 2015年全国范围内的SFTS患者相比,本研究对象的病死率较低,高热、肌痛和意识障碍的发生率也较低。