Suppr超能文献

2014 - 2018年韩国济州岛严重发热伴血小板减少综合征确诊病例的流行病学和临床特征

Epidemiological and Clinical Characteristics of Confirmed Cases of Severe Fever With Thrombocytopenia Syndrome in Jeju Province, Korea, 2014-2018.

作者信息

Kim Jinhee, Bae Jong-Myon

机构信息

Jeju Center for Infectious Diseases Control and Prevention, Jeju, Korea.

Department of Preventive Medicine, Jeju National University School of Medicine, Jeju, Korea.

出版信息

J Prev Med Public Health. 2019 May;52(3):195-199. doi: 10.3961/jpmph.18.289. Epub 2019 Apr 3.

Abstract

OBJECTIVES

Jeju Province is well known as the region showing the highest incidence of severe fever with thrombocytopenia syndrome (SFTS) in South Korea. The aim of this study was to evaluate the epidemiological and clinical characteristics of SFTS patients in Jeju Province.

METHODS

The primary data for this study were obtained from the Integrated Diseases and Health Control System of the Korea Centers for Disease Control and Prevention (KCDCIS). The selection criteria were confirmed cases of SFTS with a residence listed in Jeju Province at the time of diagnosis, reported to the KCDCIS between July 16, 2014 and November 30, 2018.

RESULTS

Of 55 confirmed cases of SFTS, the case fatality rate was 10.9% (95% confidence interval [CI], 4.1 to 22.2). The most common presenting symptoms at diagnosis of severe fever, myalgia, and diarrhea had incidences of 83.6% (95% Cl, 71.2 to 92.2), 45.5% (95% Cl, 32.0 to 59.5), and 40.0% (95% CI, 27.0 to 54.1), respectively.

CONCLUSIONS

Compared to SFTS patients nationwide in 2013-2015, the subjects of this study exhibited a lower case fatality rate and had a lower incidence of severe fever, myalgia, and confusion.

摘要

目的

济州岛是韩国严重发热伴血小板减少综合征(SFTS)发病率最高的地区。本研究旨在评估济州岛SFTS患者的流行病学和临床特征。

方法

本研究的原始数据来自韩国疾病控制与预防中心的综合疾病与健康控制系统(KCDCIS)。选择标准为2014年7月16日至2018年11月30日期间报告给KCDCIS的确诊SFTS病例,诊断时居住在济州岛。

结果

在55例确诊的SFTS病例中,病死率为10.9%(95%置信区间[CI],4.1至22.2)。诊断时最常见的症状为高热、肌痛和腹泻,发生率分别为83.6%(95%CI,71.2至92.2)、45.5%(95%CI,32.0至59.5)和40.0%(95%CI,27.0至54.1)。

结论

与2013 - 2015年全国范围内的SFTS患者相比,本研究对象的病死率较低,高热、肌痛和意识障碍的发生率也较低。

相似文献

3
Severe Fever with Thrombocytopenia Syndrome in South Korea, 2013-2015.
PLoS Negl Trop Dis. 2016 Dec 29;10(12):e0005264. doi: 10.1371/journal.pntd.0005264. eCollection 2016 Dec.
4
Pathophysiology of severe fever with thrombocytopenia syndrome and development of specific antiviral therapy.
J Infect Chemother. 2018 Oct;24(10):773-781. doi: 10.1016/j.jiac.2018.07.009. Epub 2018 Aug 8.
6
Endemic Severe Fever with Thrombocytopenia Syndrome, Vietnam.
Emerg Infect Dis. 2019 May;25(5):1029-1031. doi: 10.3201/eid2505.181463.
7
The Emergence of Severe Fever with Thrombocytopenia Syndrome Virus.
Am J Trop Med Hyg. 2017 Oct;97(4):992-996. doi: 10.4269/ajtmh.16-0967. Epub 2017 Aug 18.
8
Severe Fever with Thrombocytopenia Syndrome Virus in Ticks and SFTS Incidence in Humans, South Korea.
Emerg Infect Dis. 2020 Sep;26(9):2292-2294. doi: 10.3201/eid2609.200065.
10
Molecular genomic characterization of tick- and human-derived severe fever with thrombocytopenia syndrome virus isolates from South Korea.
PLoS Negl Trop Dis. 2017 Sep 22;11(9):e0005893. doi: 10.1371/journal.pntd.0005893. eCollection 2017 Sep.

引用本文的文献

1
The impact of climate change on ecology of tick associated with tick-borne diseases.
PLoS Comput Biol. 2025 Apr 8;21(4):e1012903. doi: 10.1371/journal.pcbi.1012903. eCollection 2025.
4
5
Seroprevalence of severe fever with thrombocytopenia syndrome using specimens from the Korea National Health & Nutrition Examination Survey.
PLoS Negl Trop Dis. 2023 Mar 22;17(3):e0011097. doi: 10.1371/journal.pntd.0011097. eCollection 2023 Mar.
7
Application of a decision tree model in the early identification of severe patients with severe fever with thrombocytopenia syndrome.
PLoS One. 2021 Jul 30;16(7):e0255033. doi: 10.1371/journal.pone.0255033. eCollection 2021.
10
Four Year Surveillance of the Vector Hard Ticks for SFTS, Ganghwa-do, Republic of Korea.
Korean J Parasitol. 2019 Dec;57(6):691-698. doi: 10.3347/kjp.2019.57.6.691. Epub 2019 Dec 31.

本文引用的文献

1
Epidemiology of severe fever and thrombocytopenia syndrome virus infection and the need for therapeutics for the prevention.
Clin Exp Vaccine Res. 2018 Jan;7(1):43-50. doi: 10.7774/cevr.2018.7.1.43. Epub 2018 Jan 29.
2
Epidemiological characteristics of scrub typhus on the Jeju Island.
Epidemiol Health. 2017 Dec 26;39:e2017060. doi: 10.4178/epih.e2017060. eCollection 2017.
3
Severe Fever with Thrombocytopenia Syndrome in South Korea, 2013-2015.
PLoS Negl Trop Dis. 2016 Dec 29;10(12):e0005264. doi: 10.1371/journal.pntd.0005264. eCollection 2016 Dec.
4
5
Fever with thrombocytopenia associated with a novel bunyavirus in China.
N Engl J Med. 2011 Apr 21;364(16):1523-32. doi: 10.1056/NEJMoa1010095. Epub 2011 Mar 16.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验