Silvas Jesus A, Aguilar Patricia V
Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, Texas.
Department of Pathology, University of Texas Medical Branch, Galveston, Texas.
Am J Trop Med Hyg. 2017 Oct;97(4):992-996. doi: 10.4269/ajtmh.16-0967. Epub 2017 Aug 18.
Severe fever with thrombocytopenia syndrome (SFTS) is a newly recognized hemorrhagic fever disease found throughout Asia with a case fatality rate between 12% and 30%. Since 2009, SFTS has been reported in China throughout 14 Chinese Provinces. In addition, SFTS has been recognized in South Korea and Japan with the first confirmed cases reported in 2012. A similar disease, caused by the closely related Heartland virus, was also reported in the United States in 2009. SFTS is caused by SFTS virus, a novel tick-borne virus in the family , genus . Unlike other mosquito- and sandfly-borne bunyaviruses, SFTS virus has not been extensively studied due to its recent emergence and many unknowns regarding its pathogenesis, life cycle, transmission, and options for therapeutics remains. In this review, we report the most current findings in SFTS virus research.
严重发热伴血小板减少综合征（SFTS）是一种新发现的出血热疾病，在亚洲各地均有发现，病死率在12%至30%之间。自2009年以来，中国14个省份均报告过SFTS病例。此外，韩国和日本也发现了SFTS，2012年报告了首例确诊病例。2009年美国也报告了一种由密切相关的心脏地带病毒引起的类似疾病。SFTS由SFTS病毒引起，它是 科 属中一种新型的蜱传病毒。与其他蚊媒和白蛉传播的布尼亚病毒不同，由于SFTS病毒最近才出现，其发病机制、生命周期、传播方式以及治疗方法仍存在许多未知之处，因此尚未得到广泛研究。在本综述中，我们报告了SFTS病毒研究的最新发现。
