Kubota Hitomi, Suzuki Yuna, Adachi Keita, Suzuki Shuhei, Hara Yukiko, Fujisaki Shigeru, Makishima Makoto, Saga Reina, Hirano Tomohiro, Sakurai Kenichi
Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.
Gan To Kagaku Ryoho. 2019 Apr;46(4):814-816.
We report here a case of a 78-year-old woman, who underwent mastectomy for breast cancer. Mammography showed a mass in the right MO area with an unclear boundary. Ultrasound examination revealed an irregular mass of 40×29×19mm in the right C region. Dynamic contrast-enhanced MRI showed a 34mm tumor with contrast effect in the C area of the right breast. We performed a core needle biopsy on the mass, and the histopathological diagnosis was apocrine carcinoma(ER-, PgR-, HER2 3+, and Ki-67 30%)of clinical T2N0M0, stageⅡA. Right mastectomy and sentinel lymph node biopsy were performed. In the postoperative pathological examination, the main lesion was apocrine carcinoma(ER-, PgR-, HER2 3+, Ki-67 20%)and Paget's disease(ER-, PgR-, HER2 3+, Ki-67 30%). After surgery, the patient was given trastuzumab therapy.
我们在此报告一例78岁女性，她因乳腺癌接受了乳房切除术。乳房X线摄影显示右乳MO区有一肿块，边界不清。超声检查发现右乳C区有一40×29×19mm的不规则肿块。动态对比增强磁共振成像显示右乳C区有一个34mm的有强化效应的肿瘤。我们对该肿块进行了粗针活检，组织病理学诊断为临床T2N0M0ⅡA期大汗腺癌（雌激素受体阴性、孕激素受体阴性、人表皮生长因子受体2 3+、Ki-67 30%）。行右乳切除术及前哨淋巴结活检。术后病理检查显示，主要病变为大汗腺癌（雌激素受体阴性、孕激素受体阴性、人表皮生长因子受体2 3+、Ki-67 20%）及佩吉特病（雌激素受体阴性、孕激素受体阴性、人表皮生长因子受体2 3+、Ki-67 30%）。术后给予患者曲妥珠单抗治疗。
