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浸渍性敷剂在住院手部感染治疗中的临床实用性:与标准护理相比的治疗效果评估。

The Clinical Utility of Maceration Dressings in the Treatment of Inpatient Hand Infections: An Evaluation of Treatment Outcomes Compared to Standard Care.

机构信息

St. Luke's University Health Network, Bethlehem, PA, USA.

出版信息

Hand (N Y). 2021 Mar;16(2):223-229. doi: 10.1177/1558944719852744. Epub 2019 Jun 5.

DOI:10.1177/1558944719852744
PMID:31165641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8041413/
Abstract

In cases of oral antibiotic-resistant infection of the hand, we propose utilizing a heated, moist maceration dressing to help shorten and simplify the in-hospital clinical course by increasing the efficacy of antibiotic deliverance to infection sites, increasing the success of nonoperative management, and decreasing eradication time of infection of the hand. Fifty-six patients older than 18 years of age who presented with hand infections requiring inpatient intravenous antibiotics at our suburban academic hospital over a 30-month period were included and randomly assigned to either the maceration dressing group or the standard treatment group. Maceration dressings included warm and moist gauze, kerlix, webril, Orthoglass, Aqua K Pad, and sling. Fifty-two patients who were mostly male and younger than 60 years of age were included. Patients who used the maceration dressing had significantly shorter hospital lengths of stay ( = .02) and intravenous antibiotics duration before transition to oral antibiotics ( = .04), and decreased need for formal operating room irrigation and debridement to obtain source control ( = .02) compared to patients treated with the standard dressing. Post-hoc analysis yielded improved outcomes when using the maceration dressing regardless of whether initial bedside incision and drainage was needed to decompress a superficial abscess or not. The maceration dressing can be used along with proper intravenous antibiotic treatment to improve the treatment course of patients with hand infections regardless of whether the patient needs an initial bedside incision and drainage or not. Therapeutic Level II.

摘要

对于手部口腔抗生素耐药性感染的病例,我们建议使用加热、湿润的浸渍敷料,通过增加抗生素在感染部位的释放效果、提高非手术管理的成功率并缩短手部感染的清除时间,来帮助缩短和简化住院临床病程。

在 30 个月的时间里,我们对在郊区学术医院接受住院静脉内抗生素治疗的手部感染的 56 名 18 岁以上患者进行了研究,并将他们随机分配到浸渍敷料组或标准治疗组。浸渍敷料包括温暖湿润的纱布、绷带、聚酯纤维网、玻璃纤维、水凝胶垫和吊带。52 名患者主要为男性且年龄小于 60 岁。与接受标准敷料治疗的患者相比,使用浸渍敷料的患者的住院时间(P =.02)和静脉抗生素治疗时间(P =.04)明显缩短,且无需正式的手术室冲洗和清创以获得源控制的需求减少(P =.02)。无论是否需要初始床边切开引流来减轻浅表脓肿的压力,进行术后分析后发现,使用浸渍敷料可改善预后。

无论患者是否需要初始床边切开引流,浸渍敷料都可以与适当的静脉内抗生素治疗一起用于改善手部感染患者的治疗过程。

治疗级别 II。

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